Overview

  • Product name

  • Description

    Rabbit polyclonal to PCYOX1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human PCYOX1 (internal sequence). The exact sequence is proprietary.
    Database link: Q9UHG3

  • Positive control

    • WB: A431 whole cell lysate. IHC-P: MDA-MB468 xenograft tissue. ICC/IF: A431 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab228879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.
IHC-P 1/100 - 1/1000.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the prenylcysteine oxidase family.
  • Post-translational
    modifications

    The protein is glycosylated at one or more potential N-glycosylation sites.
  • Cellular localization

    Lysosome.
  • Information by UniProt
  • Database links

  • Alternative names

    • EC 1.8.3.5 antibody
    • KIAA0908 antibody
    • PCL1 antibody
    • PCYOX_HUMAN antibody
    • PCYOX1 antibody
    • Prenylcysteine lyase antibody
    • Prenylcysteine oxidase 1 antibody
    • Prenylcysteine oxidase precursor antibody
    see all

Images

  • Anti-PCYOX1 antibody (ab228879) at 1/1000 dilution + A431 (human epidermoid carcinoma cell line) whole cell lysate at 30 µg

    Predicted band size: 57 kDa



    7.5% SDS-PAGE gel.

  • Paraffin-embedded MDA-MB468 xenograft tissue stained for PCYOX1 using ab228879 at 1/250 dilution in immunohistochemical analysis.

  • Methanol-fixed A431 (human epidermoid carcinoma cell line) cells stained for PCYOX1 (green) using ab228879 at 1/500 dilution in ICC/IF.

    Alpha-tubulin filaments are labeled with an anti-alpha Tubulin antibody at 1/500 dilution (red).

References

ab228879 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228879.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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