Key features and details
- Potent, selective D4 agonist
- CAS Number: 190383-31-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product namePD 168077 maleate, D4 agonist
DescriptionPotent, selective D4 agonist
Potent, selective D4 dopamine receptor agonist. Displays >400-fold selectivity over D2 and >300-fold selectivity over D3 subtypes (Ki values are 11.9, 2540, and 1050 nM for D4, D3, and D2 receptors, respectively). Reverses object recognition deficits.
This product appears to be unstable in ethanol solution.
Chemical nameN-[4-(2-Cyanophenyl)-1-piperazinyl]methyl-3-methylbenzamide maleate
Storage instructionsStore at -20°C. Please see notes section. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120568 has not yet been referenced specifically in any publications.