PD-1/PD-L1 inhibitor 1, small molecule inhibitor (ab230369)

Overview

  • Product name

    PD-1/PD-L1 inhibitor 1, small molecule inhibitor
  • Description

    Small molecule inhibitor of the PD-1/PD-L1 interaction
  • Alternative names

    • Programmed Cell Death 1/Programmed Cell Death-Ligand 1 Inhibitor 1
  • Biological description

    PD-1/PD-L1 inhibitor 1 blocks the PD-1/PD-L1 interaction with an IC50 of 6 nM in a cell-free HTRF assay.

  • Purity

    > 98%
  • CAS Number

    1675201-83-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S)-1-[[2,6-dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylic acid

  • Molecular weight

    475.86
  • Molecular formula

    C29H33NO5
  • PubChem identifier

    91663303
  • Storage instructions

    Shipped at 4°C. Store at -20°C.
  • Solubility overview

    200 mM in DMSO

    200 mM in water

    200 mM in ethanol

  • SMILES

    CC1=C(C=CC=C1COC2=CC(=C(C(=C2)OC)CN3CCCCC3C(=O)O)OC)C4=CC=CC=C4
  • Source

    Synthetic

References

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