APC Anti-PD-L2 antibody [24F.10C12] (ab270637)
Key features and details
- APC Mouse monoclonal [24F.10C12] to PD-L2
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2a
Related conjugates and formulations
Overview
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Product name
APC Anti-PD-L2 antibody [24F.10C12]
See all PD-L2 primary antibodies -
Description
APC Mouse monoclonal [24F.10C12] to PD-L2 -
Host species
Mouse -
Conjugation
APC. Ex: 645nm, Em: 660nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein corresponding to Human PD-L2.
Database link: Q9BQ51 -
Positive control
- Flow: Human stimulated monocytes (GM-CSF + IL-4) and human dendritic cells differentiated upon monocyte stimulation (GM-CSF + IL-4).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Size exclusion -
Clonality
Monoclonal -
Clone number
24F.10C12 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab270637 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt |
Use 10µl for 106 cells.
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Notes |
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Flow Cyt
Use 10µl for 106 cells. |
Target
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Function
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. -
Tissue specificity
Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. -
Sequence similarities
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Secreted; Cell membrane and Endomembrane system. - Information by UniProt
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Database links
- Entrez Gene: 80380 Human
- Omim: 605723 Human
- SwissProt: Q9BQ51 Human
- Unigene: 532279 Human
- Unigene: 617872 Human
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Alternative names
- B7 dendritic cell molecule antibody
- B7-DC antibody
- B7DC antibody
see all
Images
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Flow cytometry analysis of human dentritic cells differentiated upon monocyte stimulation (GM-CSF + IL-4) (red) and non-stimulated lymphocytes cells (black) labeling PD-L2 using ab270637. Concentration of 10 μl reagent/100μl peripheral whole blood. Surface staining.
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Flow cytometric analysis of human stimulated monocytes (GM-CSF + IL4) labeling PD-L2 using ab270637. Concentration of 10 μl reagent per million cells in 100µl of cell suspension.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab270637 has not yet been referenced specifically in any publications.