Anti-PD1 antibody [EH12.2H7] - Low endotoxin, Azide free (ab234159)
Key features and details
- Mouse monoclonal [EH12.2H7] to PD1 - Low endotoxin, Azide free
- Suitable for: Flow Cyt
- Reacts with: Human, Non human primates
- Isotype: IgG1
Related conjugates and formulations
Overview
-
Product name
Anti-PD1 antibody [EH12.2H7] - Low endotoxin, Azide free
See all PD1 primary antibodies -
Description
Mouse monoclonal [EH12.2H7] to PD1 - Low endotoxin, Azide free -
Host species
Mouse -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human, Non human primates -
Immunogen
Recombinant fragment corresponding to Human PD1.
-
Epitope
Extracellular -
Positive control
- Flow Cytometry: PHA-activated (3 days) human PBMC.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Constituent: PBS -
Carrier free
Yes -
Concentration information loading...
-
Purity
Protein A purified -
Purification notes
Purity is > 95% by SDS-PAGE. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test. -
Clonality
Monoclonal -
Clone number
EH12.2H7 -
Isotype
IgG1 -
Research areas
Associated products
-
Alternative Versions
-
Compatible Secondaries
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab234159 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use a concentration of 1 - 4 µg/ml.
|
Notes |
---|
Flow Cyt
Use a concentration of 1 - 4 µg/ml. |
Target
-
Function
Possible cell death inducer, in association with other factors. -
Involvement in disease
Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. -
Sequence similarities
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Developmental stage
Induced at programmed cell death. -
Cellular localization
Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 5133 Human
- Omim: 600244 Human
- SwissProt: Q15116 Human
- Unigene: 158297 Human
-
Alternative names
- CD279 antibody
- CD279 antigen antibody
- hPD 1 antibody
see all
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
Datasheet download
References (0)
ab234159 has not yet been referenced specifically in any publications.