Anti-PD1 antibody [J116] - Low endotoxin, Azide free (ab171267)
- Datasheet
- References
- Protocols
Overview
-
Product name
Anti-PD1 antibody [J116] - Low endotoxin, Azide free
See all PD1 primary antibodies -
Description
Mouse monoclonal [J116] to PD1 - Low endotoxin, Azide free -
Host species
Mouse -
Tested applications
Suitable for: Flow Cyt, Functional Studiesmore details -
Species reactivity
Reacts with: Human -
Immunogen
The details of the immunogen for this antibody are not available.
-
Positive control
- Human PD1-transfected cells
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: PBS -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
J116 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
-
Alternative Versions
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab171267 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use 1µg for 105-8 cells. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
| Functional Studies | Use at an assay dependent concentration. |
Target
-
Function
Possible cell death inducer, in association with other factors. -
Involvement in disease
Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. -
Sequence similarities
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Developmental stage
Induced at programmed cell death. -
Cellular localization
Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 5133 Human
- Omim: 600244 Human
- SwissProt: Q15116 Human
- Unigene: 158297 Human
-
Alternative names
- CD279 antibody
- CD279 antigen antibody
- hPD 1 antibody
see all
Images
-
![Flow Cytometry - Anti-PD1 antibody [J116] - Low endotoxin, Azide free (ab171267)](https://www.abcam.com/ps/products/171/ab171267/Images/ab171267-193611-anti-pd1-antibody-j116-flow-cytometry.jpg)
Flow Cytometry - Anti-PD1 antibody [J116] - Low endotoxin, Azide free (ab171267)Flow cytometric analysis of human PD1-transfected cells (right histogram) labeling PD1 with ab171267 (left panel: FITC, right panel: PE) compared to isotype controls (open histograms). Total viable cells were used for analysis.
Protocols
Datasheets and documents
References
ab171267 has not yet been referenced specifically in any publications.
