Anti-PD1 antibody [J116] - Low endotoxin, Azide free (ab171267)

Product name

Anti-PD1 antibody [J116] - Low endotoxin, Azide free
See all PD1 primary antibodies
Description

Mouse monoclonal [J116] to PD1 - Low endotoxin, Azide free
Host species

Mouse
Tested applications

Suitable for: Flow Cyt, Functional Studiesmore details
Species reactivity

Reacts with: Human
Immunogen

The details of the immunogen for this antibody are not available.
Positive control
- Human PD1-transfected cells

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer

Constituent: PBS
Concentration information loading...
Purity

Protein G purified
Clonality

Monoclonal
Clone number

J116
Isotype

IgG1
Light chain type

kappa
Research areas
- Cancer
- Cell Death
- Apoptosis
- Other

Our Abpromise guarantee covers the use of ab171267 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application	Abreviews	Notes
Flow Cyt		Use 1µg for 10^5-8 cells. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
Functional Studies		Use at an assay dependent concentration.

Function

Possible cell death inducer, in association with other factors.
Involvement in disease

Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
Sequence similarities

Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Developmental stage

Induced at programmed cell death.
Cellular localization

Membrane.
Target information above from: UniProt accession Q15116 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 5133 Human
- Omim: 600244 Human
- SwissProt: Q15116 Human
- Unigene: 158297 Human
Alternative names
- CD279 antibody
- CD279 antigen antibody
- hPD 1 antibody
- hPD l antibody
- hPD-1 antibody
- hSLE1 antibody
- PD 1 antibody
- PD-1 antibody
- PD1 antibody
- PDCD 1 antibody
- PDCD1 antibody
- PDCD1_HUMAN antibody
- Programmed cell death 1 antibody
- Programmed cell death 1 protein antibody
- Programmed cell death protein 1 antibody
- Protein PD 1 antibody
- Protein PD-1 antibody
- SLEB2 antibody
- Systemic lupus erythematosus susceptibility 2 antibody
see all

Flow Cytometry - Anti-PD1 antibody [J116] - Low endotoxin, Azide free (ab171267)

Flow cytometric analysis of human PD1-transfected cells (right histogram) labeling PD1 with ab171267 (left panel: FITC, right panel: PE) compared to isotype controls (open histograms). Total viable cells were used for analysis.

ab171267 has not yet been referenced specifically in any publications.

Publishing research using ab171267? Please let us know so that we can cite the reference in this datasheet.

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