Anti-PD1 antibody [J116] - Low endotoxin, Azide free (ab171267)

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Overview

  • Product name
    Anti-PD1 antibody [J116] - Low endotoxin, Azide free
    See all PD1 primary antibodies
  • Description
    Mouse monoclonal [J116] to PD1 - Low endotoxin, Azide free
  • Host species
    Mouse
  • Tested applications
    Suitable for: Flow Cyt, Functional Studiesmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control
    • Human PD1-transfected cells

Properties

Applications

Our Abpromise guarantee covers the use of ab171267 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 1µg for 105-8 cells.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
Functional Studies Use at an assay dependent concentration.

Target

  • Function
    Possible cell death inducer, in association with other factors.
  • Involvement in disease
    Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
  • Sequence similarities
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Developmental stage
    Induced at programmed cell death.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • CD279 antibody
      • CD279 antigen antibody
      • hPD 1 antibody
      • hPD l antibody
      • hPD-1 antibody
      • hSLE1 antibody
      • PD 1 antibody
      • PD-1 antibody
      • PD1 antibody
      • PDCD 1 antibody
      • PDCD1 antibody
      • PDCD1_HUMAN antibody
      • Programmed cell death 1 antibody
      • Programmed cell death 1 protein antibody
      • Programmed cell death protein 1 antibody
      • Protein PD 1 antibody
      • Protein PD-1 antibody
      • SLEB2 antibody
      • Systemic lupus erythematosus susceptibility 2 antibody
      see all

    Images

    • Flow Cytometry - Anti-PD1 antibody [J116] - Low endotoxin, Azide free (ab171267)
      Flow Cytometry - Anti-PD1 antibody [J116] - Low endotoxin, Azide free (ab171267)

      Flow cytometric analysis of human PD1-transfected cells (right histogram) labeling PD1 with ab171267 (left panel: FITC, right panel: PE) compared to isotype controls (open histograms). Total viable cells were used for analysis.

    References

    ab171267 has not yet been referenced specifically in any publications.

    Publishing research using ab171267? Please let us know so that we can cite the reference in this datasheet.

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