Overview

  • Product name

    Anti-PDE2A antibody [EPR9688]
    See all PDE2A primary antibodies
  • Description

    Rabbit monoclonal [EPR9688] to PDE2A
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human PDE2A aa 1-100 (N terminal). The exact sequence is proprietary.

  • Positive control

    • Recombinant human PDE2A protein (ab125613) can be used as a positive control in WB. Fetal brain and fetal forebrain cell lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab140650 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 106 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
    • Tissue specificity

      Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
    • Sequence similarities

      Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
      Contains 2 GAF domains.
    • Domain

      GAF 1 functions as a dimerization domain, whereas GAF 2 binds cGMP, which causes activation of the catalytic activity of the enzyme.
    • Cellular localization

      Membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • 5''-cyclic phosphodiesterase antibody
      • cGMP dependent 3'5' cyclic phosphodiesterase antibody
      • cGMP stimulated phosphodiesterase 1 antibody
      • cGMP stimulated phosphodiesterase 4 antibody
      • cGMP-dependent 3'' antibody
      • cGMP-stimulated phosphodiesterase 2 antibody
      • CGS PDE antibody
      • CGS-PDE antibody
      • cGSPDE antibody
      • Cyclic GMP stimulated phosphodiesterase antibody
      • Cyclic GMP-stimulated phosphodiesterase antibody
      • Human cGMP stimulated 3'5' cyclic nucleotide phosphodiesterase antibody
      • PDE 2A antibody
      • PDE 2A1 antibody
      • PDE 2A4 antibody
      • PDE2A antibody
      • PDE2A_HUMAN antibody
      • PDE2A1 antibody
      • PDE2A4 antibody
      • phosphodiesterase 2A antibody
      • Phosphodiesterase 2A cGMP stimulated antibody
      see all

    Images

    • All lanes : Anti-PDE2A antibody [EPR9688] (ab140650) at 1/1000 dilution

      Lane 1 : Fetal brain cell lysates
      Lane 2 : Fetal forebrain cell lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP conjugated goat anti-rabbit at 1/2000 dilution

      Predicted band size: 106 kDa

    References

    This product has been referenced in:

    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab140650.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Sign up