Overview

  • Product name
    Anti-PDE4C antibody
    See all PDE4C primary antibodies
  • Description
    Rabbit polyclonal to PDE4C
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Pig
  • Immunogen

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 325 and 637 of Human PDE4C (NP_000914).

  • Positive control
    • 293T whole cell lysate, A431, HeLaS3, and Raji cell lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 1.21% Tris, 0.75% Glycine
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab97356 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 80 kDa.

Target

  • Function
    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
  • Tissue specificity
    Expressed in various tissues but not in cells of the immune system.
  • Pathway
    Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
  • Sequence similarities
    Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
  • Information by UniProt
  • Database links
    see all
  • Alternative names
    • 5''-cyclic phosphodiesterase 4C antibody
    • cAMP specific 3' 5' cyclic phosphodiesterase 4C antibody
    • cAMP-specific 3'' antibody
    • DPDE 1 antibody
    • DPDE1 antibody
    • MGC126222 antibody
    • PDE 21 antibody
    • PDE 4C antibody
    • PDE21 antibody
    • Pde4c antibody
    • PDE4C_HUMAN antibody
    • Phosphodiesterase 4C antibody
    • Phosphodiesterase 4C cAMP specific antibody
    • Phosphodiesterase 4C, cAMP specific (phosphodiesterase E1 dunce homolog, Drosophila) antibody
    • Phosphodiesterase E1 dunce homolog antibody
    • Phosphodiesterase E1 dunce homolog Drosophila antibody
    • Phosphodiesterase type 4C antibody
    see all

Images

  • Western blot - Anti-PDE4C antibody (ab97356)
    Western blot - Anti-PDE4C antibody (ab97356)
    Anti-PDE4C antibody (ab97356) at 1/1000 dilution + 293T whole cell lysate at 30 µg

    Predicted band size: 80 kDa



    7.5% SDS PAGE

References

This product has been referenced in:
  • Fang Q  et al. PGE 2 desensitizes ß -agonist effect on human lung fibroblast-mediated collagen gel contraction through upregulating PDE4. Mediators Inflamm 2013:145197 (2013). Read more (PubMed: 24227907) »

See 1 Publication for this product

Publishing research using ab97356? Please let us know so that we can cite the reference in this datasheet.

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