Anti-PDE4C antibody (ab97356)
- Datasheet
- References (1)
- Protocols
Overview
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Product name
Anti-PDE4C antibody
See all PDE4C primary antibodies -
Description
Rabbit polyclonal to PDE4C -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow, Pig
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Immunogen
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 325 and 637 of Human PDE4C (NP_000914).
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Positive control
- 293T whole cell lysate, A431, HeLaS3, and Raji cell lysates.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab97356 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 80 kDa. |
Target
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Function
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. -
Tissue specificity
Expressed in various tissues but not in cells of the immune system. -
Pathway
Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1. -
Sequence similarities
Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. - Information by UniProt
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Database links
- Entrez Gene: 5143 Human
- Entrez Gene: 110385 Mouse
- Entrez Gene: 290646 Rat
- Omim: 600128 Human
- SwissProt: Q08493 Human
- SwissProt: Q3UEI1 Mouse
- SwissProt: P14644 Rat
- Unigene: 132584 Human
see all -
Alternative names
- 5''-cyclic phosphodiesterase 4C antibody
- cAMP specific 3' 5' cyclic phosphodiesterase 4C antibody
- cAMP-specific 3'' antibody
see all
Images
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Western blot - Anti-PDE4C antibody (ab97356)Anti-PDE4C antibody (ab97356) at 1/1000 dilution + 293T whole cell lysate at 30 µg
Predicted band size: 80 kDa
7.5% SDS PAGE
Protocols
References
This product has been referenced in:
- Fang Q et al. PGE 2 desensitizes ß -agonist effect on human lung fibroblast-mediated collagen gel contraction through upregulating PDE4. Mediators Inflamm 2013:145197 (2013). Read more (PubMed: 24227907) »
