Key features and details
- Rabbit polyclonal to PDE4C
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-PDE4C antibody
See all PDE4C primary antibodies
DescriptionRabbit polyclonal to PDE4C
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow, Pig
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 325 and 637 of Human PDE4C (NP_000914).
- 293T whole cell lysate, A431, HeLaS3, and Raji cell lysates.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab97356 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 80 kDa.|
FunctionHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Tissue specificityExpressed in various tissues but not in cells of the immune system.
PathwayPurine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
Sequence similaritiesBelongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
- Information by UniProt
- 5''-cyclic phosphodiesterase 4C antibody
- cAMP specific 3' 5' cyclic phosphodiesterase 4C antibody
- cAMP-specific 3'' antibody
ab97356 has been referenced in 1 publication.
- Fang Q et al. PGE 2 desensitizes ß -agonist effect on human lung fibroblast-mediated collagen gel contraction through upregulating PDE4. Mediators Inflamm 2013:145197 (2013). PubMed: 24227907