Key features and details
- Rabbit polyclonal to PDE4DIP
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-PDE4DIP antibody
DescriptionRabbit polyclonal to PDE4DIP
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
antigen sequence, corresponding to amino acids 525-663 of Human PDE4DIP.
- Human rectum tissue; RT 4, U 251 MG, Human liver and Human tonsil lysates.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab121275 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|WB||Use a concentration of 0.04 - 0.4 µg/ml.|
FunctionMay function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.
Tissue specificityHighly expressed in heart and skeletal muscle and to a lower extent in brain and placenta.
Involvement in diseaseNote=A chromosomal aberration involving PDE4DIP may be the cause of a myeloproliferative disorder (MBD) associated with eosinophilia. Translocation t(1;5)(q23;q33) that forms a PDE4DIP-PDGFRB fusion protein.
Sequence similaritiesContains 1 NBPF domain.
Developmental stageExpressed in fetal heart.
Cellular localizationGolgi apparatus. Cytoplasm > cytoskeleton > centrosome. Cytoplasm. Nucleus.
- Information by UniProt
- Cardiomyopathy associated protein 2 antibody
- Cardiomyopathy-associated protein 2 antibody
- CMYA2 antibody
All lanes : Anti-PDE4DIP antibody (ab121275) at 1/250 dilution
Lane 1 : RT 4 lysate
Lane 2 : U 251 MG lysate
Lane 3 : Human plasma lysate
Lane 4 : Human liver lysate
Lane 5 : Human tonsil lysate
Developed using the ECL technique.
ab121275 at 1/40 dilution staining PDE4DIP in Paraffin-embedded Human Rectum tissue by Immunohistochemistry.
ab121275 has not yet been referenced specifically in any publications.