Anti-PDE9A antibody (ab168432)
Key features and details
- Mouse polyclonal to PDE9A
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PDE9A antibody
See all PDE9A primary antibodies -
Description
Mouse polyclonal to PDE9A -
Host species
Mouse -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Recombinant full length protein, corresponding to amino acids 1-533 of Human PDE9A (NP_001001567.1).
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Positive control
- PDE9A transfected 293T cell line; HeLa cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.4
Constituent: 100% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab168432 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 68 kDa.
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ICC/IF |
Use a concentration of 10 µg/ml.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 68 kDa. |
ICC/IF
Use a concentration of 10 µg/ml. |
Target
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Function
Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. -
Tissue specificity
Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate. -
Sequence similarities
Belongs to the cyclic nucleotide phosphodiesterase family. PDE9 subfamily. -
Domain
Composed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain. -
Cellular localization
Cytoplasm. Endoplasmic reticulum; Cell projection > ruffle membrane. Cytoplasm > perinuclear region and Cell projection > ruffle membrane. Cytoplasm > perinuclear region. Golgi apparatus. Endoplasmic reticulum. - Information by UniProt
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Database links
- Entrez Gene: 5152 Human
- Entrez Gene: 18585 Mouse
- GenBank: NP_001001567.1 Human
- Omim: 602973 Human
- SwissProt: O76083 Human
- SwissProt: O76083-2 Human
- SwissProt: O70628 Mouse
- Unigene: 473927 Human
see all -
Alternative names
- 5''-cyclic phosphodiesterase 9A antibody
- cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody
- FLJ90181 antibody
see all
Images
Protocols
Datasheets and documents
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Datasheet download
References (0)
ab168432 has not yet been referenced specifically in any publications.