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Cardiovascular Blood Platelets
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Anti-PDGF AA antibody [MM0013-6D35] (ab51868)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDGF AA antibody [MM0013-6D35] (ab51868)

    Key features and details

    • Mouse monoclonal [MM0013-6D35] to PDGF AA
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG2

    You may also be interested in

    Secondary
    Product image
    Goat Anti-Mouse IgG H&L (HRP) (ab205719)
    Protein
    Recombinant human PDGF AA protein (ab9702)

    View more associated products

    Overview

    • Product name

      Anti-PDGF AA antibody [MM0013-6D35]
      See all PDGF AA primary antibodies
    • Description

      Mouse monoclonal [MM0013-6D35] to PDGF AA
    • Host species

      Mouse
    • Tested Applications & Species

      Application Species
      IHC-P
      Human
      See all applications and species data
    • Immunogen

      Recombinant full length protein (Human)

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
    • Storage buffer

      Constituent: PBS
    • Concentration information loading...
    • Purity

      Protein G purified
    • Purification notes

      The IgG fraction of culture supernatant was purified by protein G affinity chromatography
    • Clonality

      Monoclonal
    • Clone number

      MM0013-6D35
    • Isotype

      IgG2
    • Research areas

      • Cardiovascular
      • Blood
      • Platelets
      • Signal Transduction
      • Growth Factors/Hormones
      • PDGF
      • Immunology
      • Secreted Molecules
      • Other secreted molecules
      • Cancer
      • Cancer Metabolism
      • Response to hypoxia
      • Metabolism
      • Pathways and Processes
      • Metabolism processes
      • Hypoxia
      • Metabolism
      • Types of disease
      • Cancer

    Associated products

    • Compatible Secondaries

      • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
      • Goat Anti-Mouse IgG H&L (HRP) (ab205719)
    • Recombinant Protein

      • Recombinant human PDGF AA protein (ab9702)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab51868 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    IHC-P
    Human
    Application Abreviews Notes
    IHC-P
    Use at an assay dependent concentration. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.
    Notes
    IHC-P
    Use at an assay dependent concentration. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.

    Target

    • Function

      Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
    • Sequence similarities

      Belongs to the PDGF/VEGF growth factor family.
    • Domain

      The long form contains a basic insert which acts as a cell retention signal.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P04085 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 5154 Human
      • Omim: 173430 Human
      • SwissProt: P04085 Human
      • Unigene: 535898 Human
      • Alternative names

        • PDGF A antibody
        • PDGF A chain antibody
        • PDGF subunit A antibody
        • PDGF-1 antibody
        • PDGF1 antibody
        • PDGFA antibody
        • PDGFA_HUMAN antibody
        • Platelet derived growth factor alpha chain antibody
        • Platelet derived growth factor alpha isoform 2 preproprotein antibody
        • Platelet derived growth factor alpha polypeptide antibody
        • Platelet-derived growth factor A chain antibody
        • Platelet-derived growth factor alpha polypeptide antibody
        • Platelet-derived growth factor subunit A antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDGF AA antibody [MM0013-6D35] (ab51868)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDGF AA antibody [MM0013-6D35] (ab51868)

        ab51868 at 1/200 dilution staining PDGF AA in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections). Pretreatment with proteinase K is required.

      Protocols

      • Immunohistochemistry protocols

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
    • References (0)

      Publishing research using ab51868? Please let us know so that we can cite the reference in this datasheet.

      ab51868 has not yet been referenced specifically in any publications.

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