Anti-PDGF AA antibody [MM0013-6D35] (ab51868)

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Western blot - Anti-PDGF AA antibody [MM0013-6D35] (ab51868)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDGF AA antibody [MM0013-6D35] (ab51868)

Key features and details

  • Mouse monoclonal [MM0013-6D35] to PDGF AA
  • Suitable for: WB, IHC-P
  • Reacts with: Human
  • Isotype: IgG2

Overview

  • Product name

    Anti-PDGF AA antibody [MM0013-6D35]
    See all PDGF AA primary antibodies

  • Description

    Mouse monoclonal [MM0013-6D35] to PDGF AA

  • Host species

    Mouse

  • Tested applications

    Suitable for: WB, IHC-Pmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant full length protein (Human)

  • Positive control

    • WB: Human placenta tissue lysate. IHC-P: Human placenta tissue.

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab51868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
1/1000 - 1/2000. Predicted molecular weight: 24 kDa.
IHC-P
Use at an assay dependent concentration. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.
Notes
WB
1/1000 - 1/2000. Predicted molecular weight: 24 kDa.
IHC-P
Use at an assay dependent concentration. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

  • Sequence similarities

    Belongs to the PDGF/VEGF growth factor family.

  • Domain

    The long form contains a basic insert which acts as a cell retention signal.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    • Alternative names

      • PDGF A antibody
      • PDGF A chain antibody
      • PDGF subunit A antibody
      • PDGF-1 antibody
      • PDGF1 antibody
      • PDGFA antibody
      • PDGFA_HUMAN antibody
      • Platelet derived growth factor alpha chain antibody
      • Platelet derived growth factor alpha isoform 2 preproprotein antibody
      • Platelet derived growth factor alpha polypeptide antibody
      • Platelet-derived growth factor A chain antibody
      • Platelet-derived growth factor alpha polypeptide antibody
      • Platelet-derived growth factor subunit A antibody
      see all

    Images

    • Western blot - Anti-PDGF AA antibody [MM0013-6D35] (ab51868)
      Western blot - Anti-PDGF AA antibody [MM0013-6D35] (ab51868)
      Anti-PDGF AA antibody [MM0013-6D35] (ab51868) at 1/1000 dilution + Human placenta tissue lysate

      Predicted band size: 24 kDa
      Observed band size: 29 kDa why is the actual band size different from the predicted?

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDGF AA antibody [MM0013-6D35] (ab51868)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDGF AA antibody [MM0013-6D35] (ab51868)

      ab51868 at 1/200 dilution staining PDGF AA in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections). Pretreatment with proteinase K is required.

    References (0)

    Publishing research using ab51868? Please let us know so that we can cite the reference in this datasheet.

    ab51868 has not yet been referenced specifically in any publications.

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