Overview

  • Product name
    Anti-PDGF AB + BB antibody
  • Description
    Goat polyclonal to PDGF AB + BB
  • Host species
    Goat
  • Tested applications
    Suitable for: WB, Neutralisingmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Cow, Human, Pig
  • Immunogen

    Purified human PDGF-AB

  • Positive control
    • 3T3 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab34074 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
Neutralising
  • Application notes
    Neut: Use at a concentration of 10 - 20 µg/ml. In a 5 day assay, 10-20ug/ml inhibited 3T3 cell growth by 60-75% as stimulated by 10ng/ml of PDGF-AB.
    WB: Use at a concentration of 5 - 10 µg/ml. Predicted molecular weight: 124 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      Platelet-Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.
    • Cellular localization
      Secreted
    • Database links
    • Alternative names
      • Becaplermin antibody
      • c sis antibody
      • FLJ1285 antibody
      • Oncogene SIS antibody
      • PDGF 1 antibody
      • PDGF 2 antibody
      • PDGF A antibody
      • PDGF A chain antibody
      • PDGF B chain antibody
      • PDGF subunit A antibody
      • PDGF subunit B antibody
      • PDGF1 antibody
      • PDGF2 antibody
      • PDGFA antibody
      • PDGFB antibody
      • Platelet derived growth factor 2 antibody
      • Platelet derived growth factor alpha antibody
      • Platelet derived growth factor alpha chain antibody
      • Platelet derived growth factor alpha polypeptide antibody
      • Platelet derived growth factor B chain antibody
      • Platelet derived growth factor beta antibody
      • Platelet derived growth factor beta polypeptide antibody
      • Platelet derived growth factor subunit A antibody
      • Platelet derived growth factor subunit B antibody
      • SIS antibody
      • SSV antibody
      • v sis platelet derived growth factor beta polypeptide antibody
      see all

    References

    This product has been referenced in:
    • Smeda M  et al. Dual antiplatelet therapy with clopidogrel and aspirin increases mortality in 4T1 metastatic breast cancer-bearing mice by inducing vascular mimicry in primary tumour. Oncotarget 9:17810-17824 (2018). Read more (PubMed: 29707148) »
    • Choi HI  et al. The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms. J Dermatol Sci 91:60-68 (2018). WB ; Mouse . Read more (PubMed: 29678305) »
    See all 5 Publications for this product

    Customer reviews and Q&As

    Answer

    This PDGF antibody was raised against purified PDGF from human platelets.

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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