Product nameAnti-PDGF AB + BB antibody
DescriptionGoat polyclonal to PDGF AB + BB
Tested applicationsSuitable for: WB, Neutralisingmore details
Species reactivityReacts with: Mouse, Rat, Cow, Human, Pig
Purified human PDGF-AB
- 3T3 cells
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.00
Constituents: 0.184% Tris glycine, 40% Glycerol
Concentration information loading...
Purification notesPurified by DEAE chromatography.
Our Abpromise guarantee covers the use of ab34074 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 5 - 10 µg/ml. Predicted molecular weight: 124 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevancePlatelet-Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.
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This product has been referenced in:
- Smeda M et al. Dual antiplatelet therapy with clopidogrel and aspirin increases mortality in 4T1 metastatic breast cancer-bearing mice by inducing vascular mimicry in primary tumour. Oncotarget 9:17810-17824 (2018). Read more (PubMed: 29707148) »
- Choi HI et al. The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms. J Dermatol Sci 91:60-68 (2018). WB ; Mouse . Read more (PubMed: 29678305) »