Recombinant
RabMAb

Anti-PDGFR beta antibody [Y92] - C-terminal (ab32570)

Publishing research using ab32570? Please let us know so that we can cite the reference in this datasheet.

ab32570 has been referenced in 112 publications.

  • Abou-Antoun TJ  et al. Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant properties: A possible explanation for radio-therapy resistance. PLoS One 13:e0189711 (2018). PubMed: 29298329
  • Dias DO  et al. Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. Cell 173:153-165.e22 (2018). PubMed: 29502968
  • Yang Z  et al. Dicer reprograms stromal fibroblasts to a pro-inflammatory and tumor-promoting phenotype in ovarian cancer. Cancer Lett 415:20-29 (2018). PubMed: 29199004
  • Zhang J  et al. Human fibroblast growth factor-21 serves as a predictor and prognostic factor in patients with hepatitis B cirrhosis combined with adrenal insufficiency. Exp Ther Med 15:3189-3196 (2018). PubMed: 29545834
  • Arango-Lievano M  et al. Topographic Reorganization of Cerebrovascular Mural Cells under Seizure Conditions. Cell Rep 23:1045-1059 (2018). IHC (PFA fixed), WB ; Mouse . PubMed: 29694884
  • Stammnitz MR  et al. The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils. Cancer Cell 33:607-619.e15 (2018). IHC-P . PubMed: 29634948
  • Luo X  et al. Choroidal pericytes promote subretinal fibrosis after experimental photocoagulation. Dis Model Mech 11:N/A (2018). PubMed: 29622551
  • Misra A  et al. Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells. Nat Commun 9:2073 (2018). PubMed: 29802249
  • Steger CM  et al. Gene therapy with antisense oligonucleotides silencing c-myc reduces neointima formation and vessel wall thickness in a mouse model of vein graft disease. Exp Mol Pathol 105:1-9 (2018). IHC-P ; Mouse . PubMed: 29775572
  • Smyth LCD  et al. Markers for human brain pericytes and smooth muscle cells. J Chem Neuroanat 92:48-60 (2018). PubMed: 29885791
  • Costa A  et al. Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer. Cancer Cell 33:463-479.e10 (2018). IHC-P ; Human . PubMed: 29455927
  • Kramann R  et al. Parabiosis and single-cell RNA sequencing reveal a limited contribution of monocytes to myofibroblasts in kidney fibrosis. JCI Insight 3:N/A (2018). PubMed: 29720573
  • Ma Z  et al. Sorafenib and praziquantel synergistically attenuate Schistosoma japonicum-induced liver fibrosis in mice. Parasitol Res 117:2831-2839 (2018). PubMed: 29946766
  • Li J  et al. Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy. Immunity 49:178-193.e7 (2018). PubMed: 29958801
  • Liu JYW  et al. Doublecortin-expressing cell types in temporal lobe epilepsy. Acta Neuropathol Commun 6:60 (2018). PubMed: 30005693
  • Wang Y  et al. Characterization of multi-cellular dynamics of angiogenesis and vascular remodelling by intravital imaging of the wounded mouse cornea. Sci Rep 8:10672 (2018). PubMed: 30006556
  • Mori da Cunha MGMC  et al. Fate of mesoangioblasts in a vaginal birth injury model: influence of the route of administration. Sci Rep 8:10604 (2018). PubMed: 30006567
  • Zhou YF  et al. Sema3E/PlexinD1 inhibition is a therapeutic strategy for improving cerebral perfusion and restoring functional loss after stroke in aged rats. Neurobiol Aging 70:102-116 (2018). PubMed: 30007159
  • Hackett AR  et al. Injury type-dependent differentiation of NG2 glia into heterogeneous astrocytes. Exp Neurol 308:72-79 (2018). PubMed: 30008424
  • Coll M  et al. Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis. Cell Stem Cell 23:101-113.e7 (2018). PubMed: 30049452
  • Khaksar M  et al. High glucose condition limited the angiogenic/cardiogenic capacity of murine cardiac progenitor cells in in vitro and in vivo milieu. Cell Biochem Funct N/A:N/A (2018). PubMed: 30051492
  • Assis-Nascimento P  et al. EphB3 signaling induces cortical endothelial cell death and disrupts the blood-brain barrier after traumatic brain injury. Cell Death Dis 9:7 (2018). Mouse . PubMed: 29311672
  • Barrera V  et al. Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina. Elife 7:N/A (2018). PubMed: 29578406
  • Liu J  et al. Nestin-expressing cell types in the temporal lobe and hippocampus: Morphology, differentiation, and proliferative capacity. Glia 66:62-77 (2018). IHC-P ; Human . PubMed: 28925561
  • Le Bras A  et al. Adventitial Sca1+ Cells Transduced With ETV2 Are Committed to the Endothelial Fate and Improve Vascular Remodeling After Injury. Arterioscler Thromb Vasc Biol 38:232-244 (2018). PubMed: 29191922
  • Zhang J  et al. Culture media-based selection of endothelial cells, pericytes, and perivascular-resident macrophage-like melanocytes from the young mouse vestibular system. Hear Res 345:10-22 (2017). PubMed: 28087417
  • Assinck P  et al. Myelinogenic Plasticity of Oligodendrocyte Precursor Cells following Spinal Cord Contusion Injury. J Neurosci 37:8635-8654 (2017). PubMed: 28760862
  • Chen J  et al. CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development. Proc Natl Acad Sci U S A 114:E7622-E7631 (2017). PubMed: 28827364
  • Lu H  et al. Decreased phosphorylation of PDGFR-ß impairs the angiogenic potential of expanded endothelial progenitor cells via the inhibition of PI3K/Akt signaling. Int J Mol Med 39:1492-1504 (2017). WB ; Human . PubMed: 28487975
  • Tian L  et al. Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming. Nature 544:250-254 (2017). IHC-Fr ; Mouse . PubMed: 28371798
  • Jiang R  et al. The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion. Nat Commun 8:15129 (2017). IP . PubMed: 28541302
  • Laronda MM  et al. A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice. Nat Commun 8:15261 (2017). IHC . PubMed: 28509899
  • Hu Y  et al. Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-?B signaling pathway after LPS treatment in neonatal rats. Oncotarget 8:31638-31654 (2017). PubMed: 28404943
  • Mazza G  et al. Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation-decellularization. Sci Rep 7:5534 (2017). PubMed: 28717194
  • Murray IR  et al. av integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis. Nat Commun 8:1118 (2017). PubMed: 29061963
  • Romi MM  et al. Uric acid causes kidney injury through inducing fibroblast expansion, Endothelin-1 expression, and inflammation. BMC Nephrol 18:326 (2017). PubMed: 29089036
  • Fang M  et al. Metformin treatment after the hypoxia-ischemia attenuates brain injury in newborn rats. Oncotarget 8:75308-75325 (2017). PubMed: 29088867
  • Yang Z  et al. Reprogramming of stromal fibroblasts by SNAI2 contributes to tumor desmoplasia and ovarian cancer progression. Mol Cancer 16:163 (2017). PubMed: 29041931
  • Gonçalves AF  et al. Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells. Nat Commun 8:1466 (2017). PubMed: 29133867
  • Choi JA  et al. The anti-ALS drug riluzole attenuates pericyte loss in the diabetic retinopathy of streptozotocin-treated mice. Toxicol Appl Pharmacol 315:80-89 (2017). PubMed: 27939241
  • Xu L  et al. Different Angiogenic Potentials of Mesenchymal Stem Cells Derived from Umbilical Artery, Umbilical Vein, and Wharton's Jelly. Stem Cells Int 2017:3175748 (2017). PubMed: 28874910
  • Wang Y  et al. Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity. Development 144:3590-3601 (2017). PubMed: 28851707
  • McLane LE  et al. Loss of Tuberous Sclerosis Complex1 in Adult Oligodendrocyte Progenitor Cells Enhances Axon Remyelination and Increases Myelin Thickness after a Focal Demyelination. J Neurosci 37:7534-7546 (2017). PubMed: 28694334
  • Daquinag AC  et al. Non-glycanated Decorin Is a Drug Target on Human Adipose Stromal Cells. Mol Ther Oncolytics 6:1-9 (2017). IHC-P . PubMed: 28607949
  • Morland C  et al. Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1. Nat Commun 8:15557 (2017). PubMed: 28534495
  • Dong N  et al. MicroRNA-182 prevents vascular smooth muscle cell dedifferentiation via FGF9/PDGFRß signaling. Int J Mol Med 39:791-798 (2017). WB . PubMed: 28259995
  • Liu F  et al. Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathway. Oncotarget 8:22059-22075 (2017). Human . PubMed: 28423550
  • Dieriks BV  et al. a-synuclein transfer through tunneling nanotubes occurs in SH-SY5Y cells and primary brain pericytes from Parkinson's disease patients. Sci Rep 7:42984 (2017). IHC-P ; Human . PubMed: 28230073
  • Zhao W  et al. Mechanisms responsible for the inhibitory effects of epothilone B on scar formation after spinal cord injury. Neural Regen Res 12:478-485 (2017). IHC ; Rat . PubMed: 28469665
  • Wymeersch FJ  et al. Position-dependent plasticity of distinct progenitor types in the primitive streak. Elife 5:e10042 (2016). IHC-Fr ; Mouse . PubMed: 26780186
  • Funk LH  et al. Tumor necrosis factor superfamily member APRIL contributes to fibrotic scar formation after spinal cord injury. J Neuroinflammation 13:87 (2016). IHC . PubMed: 27098833
  • Bassett EA  et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. Elife 5:N/A (2016). PubMed: 27823583
  • Leca J  et al. Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness. J Clin Invest 126:4140-4156 (2016). Mouse, Human . PubMed: 27701147
  • Zhang T  et al. CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment. Nat Commun 7:11674 (2016). IF . PubMed: 27241286
  • Samura M  et al. Combinatorial Treatment with Apelin-13 Enhances the Therapeutic Efficacy of a Preconditioned Cell-Based Therapy for Peripheral Ischemia. Sci Rep 6:19379 (2016). WB, ICC . PubMed: 26763337
  • Kobayashi H  et al. Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin. J Clin Invest 126:1926-38 (2016). PubMed: 27088801
  • Daquinag AC  et al. Targeted Proapoptotic Peptides Depleting Adipose Stromal Cells Inhibit Tumor Growth. Mol Ther 24:34-40 (2016). PubMed: 26316391
  • Thériault P  et al. High fat diet exacerbates Alzheimer's disease-related pathology in APPswe/PS1 mice. Oncotarget 7:67808-67827 (2016). WB . PubMed: 27661129
  • Chen X  et al. Low Dose Cadmium Inhibits Proliferation of Human Renal Mesangial Cells via Activation of the JNK Pathway. Int J Environ Res Public Health 13: (2016). ICC/IF ; Human . PubMed: 27739415
  • Hackett AR  et al. STAT3 and SOCS3 regulate NG2 cell proliferation and differentiation after contusive spinal cord injury. Neurobiol Dis 89:10-22 (2016). PubMed: 26804026
  • van Dijk CG  et al. Distinct Endothelial Cell Responses in the Heart and Kidney Microvasculature Characterize the Progression of Heart Failure With Preserved Ejection Fraction in the Obese ZSF1 Rat With Cardiorenal Metabolic Syndrome. Circ Heart Fail 9:e002760 (2016). PubMed: 27056881
  • Arfian N  et al. Vitamin D Attenuates Kidney Fibrosis via Reducing Fibroblast Expansion, Inflammation, and Epithelial Cell Apoptosis. Kobe J Med Sci 62:E38-44 (2016). PubMed: 27578035
  • Li X  et al. Regenerative Potential of Ependymal Cells for Spinal Cord Injuries Over Time. EBioMedicine 13:55-65 (2016). PubMed: 27818039
  • Hartmann DA  et al. Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice. Neurophotonics 2:041402 (2015). PubMed: 26158016
  • Daquinag AC  et al. Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development. Cell Death Differ 22:351-63 (2015). PubMed: 25342467
  • Zhu Y  et al. Fibronectin Matrix Assembly after Spinal Cord Injury. J Neurotrauma 32:1158-67 (2015). PubMed: 25492623
  • Bei Y  et al. Cardiac telocytes and fibroblasts in primary culture: different morphologies and immunophenotypes. PLoS One 10:e0115991 (2015). ICC/IF ; Mouse . PubMed: 25693182
  • Shankman LS  et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med 21:628-37 (2015). IF ; Mouse . PubMed: 25985364
  • Lorusso B  et al. Isolation and Characterization of Human Lung Lymphatic Endothelial Cells. Biomed Res Int 2015:747864 (2015). ICC/IF ; Human . PubMed: 26137493
  • Sheikh AQ  et al. Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension. Sci Transl Med 7:308ra159 (2015). IHC ; Mouse . PubMed: 26446956
  • Nurnberg ST  et al. Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap. PLoS Genet 11:e1005155 (2015). Mouse . PubMed: 26020946
  • Zhou Q  et al. Cardiac telocytes are double positive for CD34/PDGFR-a. J Cell Mol Med 19:2036-42 (2015). PubMed: 26082061
  • Stanton GB  et al. Cytogenesis in the adult monkey motor cortex: perivascular NG2 cells are the major adult born cell type. J Comp Neurol 523:849-68 (2015). PubMed: 25308320
  • Chen SY  et al. Isolation and characterization of mesenchymal progenitor cells from human orbital adipose tissue. Invest Ophthalmol Vis Sci 55:4842-52 (2014). IF ; Human . PubMed: 24994870
  • Yang Y  et al. Telocytes in human heart valves. J Cell Mol Med 18:759-65 (2014). IHC-Fr ; Human . PubMed: 24674389
  • Fetting JL  et al. FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney. Development 141:17-27 (2014). Mouse . PubMed: 24284212
  • Richard L  et al. Characterization of Endoneurial Fibroblast-like Cells from Human and Rat Peripheral Nerves. J Histochem Cytochem 62:424-435 (2014). PubMed: 24670794
  • Starke C  et al. Renin Lineage Cells Repopulate the Glomerular Mesangium after Injury. J Am Soc Nephrol N/A:N/A (2014). PubMed: 24904091
  • Isasi E  et al. Increased blood-brain barrier permeability and alterations in perivascular astrocytes and pericytes induced by intracisternal glutaric acid. Fluids Barriers CNS 11:15 (2014). IHC-FrFl ; Rat . PubMed: 25077029
  • Niu F  et al. Tat 101-mediated enhancement of brain pericyte migration involves platelet-derived growth factor subunit B homodimer: implications for human immunodeficiency virus-associated neurocognitive disorders. J Neurosci 34:11812-25 (2014). WB, ICC/IF, IHC-P . PubMed: 25164676
  • Bedekovics J  et al. Image analysis of platelet derived growth factor receptor-beta (PDGFRß) expression to determine the grade and dynamics of myelofibrosis in bone marrow biopsy samples. Cytometry B Clin Cytom 86:319-28 (2014). Human . PubMed: 24810671
  • Wang F  et al. Telocytes in liver regeneration: possible roles. J Cell Mol Med 18:1720-6 (2014). IHC-Fr ; Mouse . PubMed: 25130653
  • Geng ZM  et al. Activated human hepatic stellate cells promote growth of human hepatocellular carcinoma in a subcutaneous xenograft nude mouse model. Cell Biochem Biophys 70:337-47 (2014). PubMed: 24676678
  • Zhao Y  et al. Isolation and epithelial co-culture of mouse renal peritubular endothelial cells. BMC Cell Biol 15:40 (2014). PubMed: 25433516
  • Ciucurel EC & Sefton MV Del-1 overexpression in endothelial cells increases vascular density in tissue-engineered implants containing endothelial cells and adipose-derived mesenchymal stromal cells. Tissue Eng Part A 20:1235-52 (2014). PubMed: 24151812
  • Shankar GM  et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathol Commun 2:167 (2014). IHC . PubMed: 25589003
  • Milesi S  et al. Redistribution of PDGFRß cells and NG2DsRed pericytes at the cerebrovasculature after status epilepticus. Neurobiol Dis 71C:151-158 (2014). PubMed: 25088711
  • Xiao J  et al. Telocytes in liver: electron microscopic and immunofluorescent evidence. J Cell Mol Med 17:1537-42 (2013). PubMed: 24266938
  • Raha AA  et al. The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer's disease. Acta Neuropathol Commun 1:55 (2013). PubMed: 24252754
  • Kan L  et al. Glast-expressing progenitor cells contribute to heterotopic ossification. Bone 53:194-203 (2013). PubMed: 23262027
  • Cisbani G  et al. Striatal allografts in patients with Huntington's disease: impact of diminished astrocytes and vascularization on graft viability. Brain 136:433-43 (2013). IHC-FoFr ; Human . PubMed: 23378216
  • Vasefi MS  et al. 5-Hydroxytryptamine type 7 receptor neuroprotection against NMDA-induced excitotoxicity is PDGFß receptor dependent. J Neurochem 125:26-36 (2013). PubMed: 23336565
  • Steinberg F  et al. A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport. Nat Cell Biol 15:461-71 (2013). PubMed: 23563491
  • Yamazaki S  et al. A mouse model of adult-onset anaemia due to erythropoietin deficiency. Nat Commun 4:1950 (2013). PubMed: 23727690
  • Zhu J  et al. A Fibronectin Peptide Redirects PDGF-BB/PDGFR Complexes to Macropinocytosis-Like Internalization and Augments PDGF-BB Survival Signals. J Invest Dermatol N/A:N/A (2013). Human . PubMed: 24304816
  • Smith NR  et al. Tumor stromal architecture can define the intrinsic tumor response to VEGF-targeted therapy. Clin Cancer Res 19:6943-56 (2013). IHC-P ; Human . PubMed: 24030704
  • Bai L  et al. Myelin repair and functional recovery mediated by neural cell transplantation in a mouse model of multiple sclerosis. Neurosci Bull 29:239-50 (2013). PubMed: 23471865
  • Neng L  et al. Isolation and culture of endothelial cells, pericytes and perivascular resident macrophage-like melanocytes from the young mouse ear. Nat Protoc 8:709-20 (2013). ICC/IF . PubMed: 23493068
  • Hewitt KJ  et al. PDGFRß expression and function in fibroblasts derived from pluripotent cells is linked to DNA demethylation. J Cell Sci 125:2276-87 (2012). Human . PubMed: 22344267
  • Spitzer TL  et al. Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype. Biol Reprod 86:58 (2012). PubMed: 22075475
  • Smith MJ  et al. Heterogeneity of vascular and progenitor cell compartments in tumours from MMTV-PyVmT transgenic mice during mammary cancer progression. Int J Exp Pathol 92:106-16 (2011). IHC-P ; Mouse . PubMed: 21059124
  • Jeansson M  et al. Angiopoietin-1 is essential in mouse vasculature during development and in response to injury. J Clin Invest 121:2278-89 (2011). IHC-P, IHC-Fr ; Mouse . PubMed: 21606590
  • Yaguchi T  et al. Urinary trypsin inhibitor suppresses migration of malignant mesothelioma. Cancer Lett 288:214-8 (2010). PubMed: 19660858
  • Qayum N  et al. Tumor vascular changes mediated by inhibition of oncogenic signaling. Cancer Res 69:6347-54 (2009). PubMed: 19622766
  • Miyata M  et al. Regulation by afadin of cyclical activation and inactivation of Rap1, Rac1, and RhoA small G proteins at leading edges of moving NIH3T3 cells. J Biol Chem 284:24595-609 (2009). ICC/IF ; Mouse . PubMed: 19589776
  • Miyata M  et al. Localization of nectin-free afadin at the leading edge and its involvement in directional cell movement induced by platelet-derived growth factor. J Cell Sci 122:4319-29 (2009). PubMed: 19887591
  • Amano H  et al. Interaction and localization of Necl-5 and PDGF receptor beta at the leading edges of moving NIH3T3 cells: Implications for directional cell movement. Genes Cells 13:269-84 (2008). PubMed: 18298801
  • Kanzaki N  et al. Involvement of the nectin-afadin complex in PDGF-induced cell survival. J Cell Sci 121:2008-17 (2008). WB ; Mouse . PubMed: 18505795
  • Takahashi M  et al. Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells. Genes Cells 13:549-69 (2008). PubMed: 18422604
  • Kazlauskas A & Cooper JA Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins. Cell 58:1121-33 (1989). PubMed: 2550144
  • Deuel TF  et al. Platelet-derived growth factor: a multifunctional regulator of normal and abnormal cell growth. Biofactors 1:213-7 (1988). PubMed: 2855705
  • Deuel TF & Huang JS Platelet-derived growth factor. Structure, function, and roles in normal and transformed cells. J Clin Invest 74:669-76 (1984). PubMed: 6088582

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