Overview

  • Product name

  • Description

    Goat polyclonal to PDIA2/PDIP
  • Host species

    Goat
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human PDIA2/PDIP aa 129-141 (internal sequence) (Cysteine residue). NP_006840.2
    Sequence:

    C-THPEEYTGPRDAE


    Database link: Q13087

  • Positive control

    • WB: Human pancreas lysate.
  • General notes

     This product was previously labelled as PDIA2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab223670 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 58.2 kDa).

Target

  • Function

    Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
  • Tissue specificity

    Highly expressed in pancreas (at protein level).
  • Sequence similarities

    Belongs to the protein disulfide isomerase family.
    Contains 2 thioredoxin domains.
  • Post-translational
    modifications

    The disulfide-linked homodimer exhibits an enhanced chaperone activity.
    Glycosylated.
  • Cellular localization

    Endoplasmic reticulum lumen.
  • Information by UniProt
  • Database links

  • Alternative names

    • Pancreas specific protein disulfide isomerase antibody
    • Pancreas-specific protein disulfide isomerase antibody
    • Pancreatic protein disulfide isomerase antibody
    • PDA2 antibody
    • PDI antibody
    • PDIA2 antibody
    • PDIA2_HUMAN antibody
    • PDIp antibody
    • PDIR antibody
    • Protein disulfide isomerase A2 antibody
    • Protein disulfide isomerase antibody
    • Protein disulfide isomerase associated 2 antibody
    • Protein disulfide isomerase family A member 2 antibody
    • Protein disulfide isomerase pancreatic antibody
    • Protein disulfide-isomerase A2 antibody
    • Rho GDP dissociation inhibitor gamma antibody
    see all

Images

  • Anti-PDIA2/PDIP antibody (ab223670) at 0.03 µg/ml + human pancreas lysate at 35 µg

    Developed using the ECL technique.

    Predicted band size: 58.2 kDa
    Additional bands at: 70 kDa (possible glycosylated form)



    Primary incubation was 1 hour.

References

ab223670 has not yet been referenced specifically in any publications.

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