Validated using a knockout cell line
Recombinant
RabMAb

Recombinant Anti-PDK1 antibody [EPR13009] - BSA and Azide free (ab249846)

Overview

  • Product name
    Anti-PDK1 antibody [EPR13009] - BSA and Azide free
    See all PDK1 primary antibodies
  • Description
    Rabbit monoclonal [EPR13009] to PDK1 - BSA and Azide free
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC/IF or IHC-P
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human PDK1 aa 1-100 (Cysteine residue). The exact sequence is proprietary.
    Database link: Q15118

  • General notes

    ab249846 is a PBS-only buffer format of ab175190. Please refer to ab175190 for recommended dilutions, protocols, and image data.

     

     This product was previously labelled as Mitochondrial Pyruvate dehydrogenase kinase 1

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Applications

Our Abpromise guarantee covers the use of ab249846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 49 kDa.
IP Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
  • Target

    • Function
      Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
    • Tissue specificity
      Expressed predominantly in the heart.
    • Sequence similarities
      Belongs to the PDK/BCKDK protein kinase family.
      Contains 1 histidine kinase domain.
    • Cellular localization
      Mitochondrion matrix.
    • Information by UniProt
    • Database links
    • Alternative names
      • [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial antibody
      • HGNC:8809 antibody
      • Mitochondrial pyruvate dehydrogenase kinase isoenzyme 1 antibody
      • PDH kinase 1 antibody
      • Pdk1 antibody
      • PDK1_HUMAN antibody
      • Pyruvate dehydrogenase kinase isoform 1 antibody
      • Pyruvate dehydrogenase kinase, isoenzyme 1 antibody
      see all

    References

    ab249846 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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