Overview

  • Product name

    Anti-PDLIM2 antibody - N-terminal
    See all PDLIM2 primary antibodies
  • Description

    Rabbit polyclonal to PDLIM2 - N-terminal
  • Host species

    Rabbit
  • Specificity

    ab198244 detects endogenous level of total PDLIM2 protein.
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Fusion protein within Human PDLIM2 (N terminal). The exact sequence is proprietary. Fusion protein corresponding to residues near the N terminal of human PDLIM2. NCBI Accession No. BC021556. The identity of the protein fusion partner is GST.
    Database link: Q96JY6

  • Positive control

    • Mouse liver tissue lysate and Human cervical cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab198244 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/1000. Predicted molecular weight: 37 kDa.
IHC-P 1/15 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity.
  • Sequence similarities

    Contains 1 LIM zinc-binding domain.
    Contains 1 PDZ (DHR) domain.
  • Cellular localization

    Cytoplasm > cytoskeleton; Nucleus; Cytoplasm. Nucleus. May be partially nuclear and Cytoplasm > cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ34715 antibody
    • MYSTIQUE antibody
    • OTTHUMP00000162522 antibody
    • OTTHUMP00000205197 antibody
    • OTTHUMP00000205198 antibody
    • OTTHUMP00000205199 antibody
    • OTTHUMP00000205200 antibody
    • OTTHUMP00000205202 antibody
    • OTTHUMP00000205203 antibody
    • PDLI2_HUMAN antibody
    • Pdlim2 antibody
    • PDZ and LIM domain 2 (mystique) antibody
    • PDZ and LIM domain protein 2 antibody
    • PDZ-LIM protein mystique antibody
    • SLIM antibody
    • Stat-interacting LIM protein antibody
    see all

Images

  • Anti-PDLIM2 antibody - N-terminal (ab198244) at 1/250 dilution + mouse liver tissue lysate at 40 µg

    Predicted band size: 37 kDa



    8%SDS-PAGE

  • Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling PDLIM2 using ab198244 at a 1/20 dilution.

References

ab198244 has not yet been referenced specifically in any publications.

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