Overview

  • Product name

  • Description

    Rabbit polyclonal to PDP2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 287-336 (CRAILGVQED NGMWSCLPLT RDHNAWNQAE LSRLKREHPE SEDRTIIMED) of Human PDP2 (NP_065837).

  • Positive control

    • Jurkat cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab99170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 60 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function

    Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
  • Sequence similarities

    Belongs to the PP2C family.
  • Cellular localization

    Mitochondrion matrix.
  • Information by UniProt
  • Database links

  • Alternative names

    • [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2 antibody
    • KIAA1348 antibody
    • mitochondrial antibody
    • PDP 2 antibody
    • Pdp2 antibody
    • PDP2_HUMAN antibody
    • PDPC 2 antibody
    • PPM2B antibody
    • PPM2C2 antibody
    • Protein phosphatase 2C magnesium dependent catalytic subunit 2 antibody
    • Protein phosphatase Mg2+/Mn2+ dependent 2B antibody
    • Pyruvate dehydrogenase phosphatase 2 antibody
    • Pyruvate dehydrogenase phosphatase catalytic subunit 2 antibody
    • pyruvate dehydrogenase phosphatase isoenzyme 2 antibody
    • Pyruvate dehydrogenase phosphatase, catalytic subunit 2 antibody
    see all

Images

  • Anti-PDP2 antibody (ab99170) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size: 60 kDa



    Gel concentration: 12%

References

This product has been referenced in:

  • Pendleton AL  et al. Increased pyruvate dehydrogenase activity in skeletal muscle of growth-restricted ovine fetuses. Am J Physiol Regul Integr Comp Physiol 317:R513-R520 (2019). Read more (PubMed: 31314546) »
See 1 Publication for this product

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