Overview

  • Product name

  • Description

    Rabbit polyclonal to PDSS2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human PDSS2 aa 20-70 conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Sequence:

    PRRLWWSPSLD TISSVGSWRG RSSKSPAHWN QVVSEAEKIV GYPTSFMSLR


    Database link: Q86YH6

  • Positive control

    • Human kidney tissue; Rat brain lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab203064 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

When using a fluorescent probe the recommended dilution is 1/50 – 1/200.

WB 1/100 - 1/1000. Predicted molecular weight: 44 kDa.

Target

  • Function

    Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.
  • Pathway

    Cofactor biosynthesis; ubiquinone biosynthesis.
  • Involvement in disease

    Defects in PDSS2 are a cause of coenzyme Q10 deficiency (COQ10D) [MIM:607426]. Coenzyme Q10 deficiency is an autosomal recessive disorder with variable manifestations. It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy.
  • Sequence similarities

    Belongs to the FPP/GGPP synthase family.
  • Cellular localization

    Mitochondrion.
  • Information by UniProt
  • Database links

  • Alternative names

    • All-trans-decaprenyl-diphosphate synthase subunit 2 antibody
    • bA59I9.3 antibody
    • C6orf210 antibody
    • Candidate tumor suppressor protein antibody
    • chromosome 6 open reading frame 210 antibody
    • Decaprenyl pyrophosphate synthase subunit 2 antibody
    • decaprenyl pyrophosphate synthetase subunit 2 antibody
    • Decaprenyl-diphosphate synthase subunit 2 antibody
    • DLP1 antibody
    • DLP1_HUMAN antibody
    • hDLP1 antibody
    • Pdss2 antibody
    • prenyl (decaprenyl) diphosphate synthase, subunit 2 antibody
    • subunit 2 of decaprenyl diphosphate synthase antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labeling PDSS2 with ab203064 at 1/200 dilution with DAB staining.

  • Anti-PDSS2 antibody (ab203064) at 1/200 dilution + Rat brain lysate

    Predicted band size: 44 kDa

References

ab203064 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab203064.
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