Key features and details
- Rabbit polyclonal to PDZD3
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-PDZD3 antibody
DescriptionRabbit polyclonal to PDZD3
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Recombinant fragment corresponding to Human PDZD3 aa 42-291.
Database link: Q86UT5
- WB: Mouse kidney and heart tissue lysate. IHC-P: Human skin and kidney tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.03% Proclin 300
Concentration information loading...
PurityProtein G purified
Purification notesPurity >95%
Our Abpromise guarantee covers the use of ab235412 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
|WB||1/500 - 1/1000. Predicted molecular weight: 61 kDa.|
FunctionActs as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.
Tissue specificityExpressed in kidney and the gastrointestinal tract. Not detected in brain, heart, skeletal muscle or cells of hematopoietic origin.
Sequence similaritiesContains 4 PDZ (DHR) domains.
Cellular localizationCell membrane. Cytoplasm. Preferentially accumulates at the apical surface and ileal brush border of intestinal epithelial cells.
- Information by UniProt
- IKEPP antibody
- Intestinal and kidney enriched PDZ protein antibody
- Intestinal and kidney-enriched PDZ protein antibody
Paraffin-embedded human skin tissue stained for PDZD3 using ab235412 at 1/100 dilution in immunohistochemical analysis.
All lanes : Anti-PDZD3 antibody (ab235412) at 1/500 dilution
Lane 1 : Mouse kidney tissue lysate
Lane 2 : Mouse heart tissue lysate
All lanes : Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 61 kDa
Paraffin-embedded human kidney tissue stained for PDZD3 using ab235412 at 1/100 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab235412 has not yet been referenced specifically in any publications.