Overview

  • Product name
    Anti-PDZD7 antibody
  • Description
    Mouse polyclonal to PDZD7
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Orangutan
  • Immunogen

    Full length protein, corresponding to amino acids 1-511 of Human PDZD7 (AAH29054.1).

  • Positive control
    • PDZD7 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab169060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa.

Target

  • Tissue specificity
    Weakly expressed in the inner ear. Expressed in the retinal pigment epithelium.
  • Involvement in disease
    Note=A chromosomal aberration disrupting PDZD7 has been found in patients with non-syndromic sensorineural deafness. Translocation t(10;11),t(10;11).
    Defects in PDZD7 are a cause of Usher syndrome type 2C (USH2C) [MIM:605472]. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa with sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH2 is characterized by congenital mild hearing impairment with normal vestibular responses. Note=PDZD7 mutations have been found in combination with mutations in USH2A and GPR98 in patients affected by Usher syndrome, suggesting a role as contributor to digenic Usher syndrome or a modifier of retinal disease expression.
  • Sequence similarities
    Contains 2 PDZ (DHR) domains.
  • Cellular localization
    Cell projection > cilium. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 9130207N01 antibody
    • EG435601 antibody
    • OTTMUSP00000044304 antibody
    • OTTMUSP00000044305 antibody
    • PDZ domain containing 7 antibody
    • PDZ domain-containing protein 7 antibody
    • PDZD7 antibody
    • PDZD7_HUMAN antibody
    • PDZK7 antibody
    • RP11-108L7.9 antibody
    see all

Images

  • All lanes : Anti-PDZD7 antibody (ab169060) at 1 µg/ml

    Lane 1 : PDZD7 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Secondary
    All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Developed using the ECL technique.

    Predicted band size: 55 kDa

References

ab169060 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab169060.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up