PE Anti-CD14 antibody [Tuk4] (ab186689)
Key features and details
- PE Mouse monoclonal [Tuk4] to CD14
- Reacts with: Sheep, Rabbit, Goat, Cow, Cat, Dog, Human, Pig, Mink, Cynomolgus monkey, Llama
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
Overview
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Product name
PE Anti-CD14 antibody [Tuk4]
See all CD14 primary antibodies -
Description
PE Mouse monoclonal [Tuk4] to CD14 -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Species reactivity
Reacts with: Sheep, Rabbit, Goat, Cow, Cat, Dog, Human, Pig, Mink, Cynomolgus monkey, Llama -
Immunogen
The details of the immunogen for this antibody are not available.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at +4°C. Do Not Freeze. Store In the Dark. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituents: 93% PBS, 5% Sucrose, 1% BSA -
Concentration information loading... -
Purity
Protein G purified -
Purification notes
Purified from Tissue culture supernatant. -
Clonality
Monoclonal -
Clone number
Tuk4 -
Isotype
IgG2a -
Research areas
Associated products
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Isotype control
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Recombinant Protein
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Related Products
Target
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Function
Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. -
Tissue specificity
Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. -
Sequence similarities
Contains 11 LRR (leucine-rich) repeats. -
Post-translational
modificationsN- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 929 Human
- Entrez Gene: 100037938 Pig
- Omim: 158120 Human
- SwissProt: Q95122 Cow
- SwissProt: P08571 Human
- Unigene: 163867 Human
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Alternative names
- CD 14 antibody
- CD_antigen=CD14 antibody
- CD14 antibody
see all
References (1)
ab186689 has been referenced in 1 publication.
- Wang Y et al. Silence of TGF-ß1 gene expression reduces prrsv replication and potentiates immunity of immune cells of tibetan pig. Vet Anim Sci 8:100074 (2019). PubMed: 32734091
