Key features and details
- PE Rat monoclonal [FCR 4G8] to CD16+CD32
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2b
Product namePE Anti-CD16+CD32 antibody [FCR 4G8]
See all CD16+CD32 primary antibodies
DescriptionPE Rat monoclonal [FCR 4G8] to CD16+CD32
ConjugationPE. Ex: 488nm, Em: 575nm
Species reactivityReacts with: Mouse
PU5 1.8 IOE7 Balb/c cell line (Mouse)
ab24537 recognises an epitope expressed by the murine low affinity Fc receptors, Fc gamma III (CD16) and Fc gamma II (CD32).
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityProtein G purified
Primary antibody notesab24537 recognises an epitope expressed by the murine low affinity Fc receptors, Fc gamma III (CD16) and Fc gamma II (CD32).
Clone numberFCR 4G8
RelevanceFunction: Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. Tissue specificity: Found on monocytes, neutrophils and eosinophil platelets. Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. PTM: Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
Cellular localizationCD32: Type I membrane protein. CD16: Attached to the membrane by a GPI anchor. Exists also as a soluble receptor, produced by a proteolytic cleavage.
- CD16a antibody
- CD16b antibody
- CD32 antibody
ab24537 has been referenced in 1 publication.
- Olme CH et al. Live cell detection of chromosome 2 deletion and Sfpi1/PU1 loss in radiation-induced mouse acute myeloid leukaemia. Leuk Res 37:1374-82 (2013). Flow Cyt ; Mouse . PubMed: 23806234