PE Anti-CD19 antibody [MB19-1] (ab93562)
![Flow Cytometry - PE Anti-CD19 antibody [MB19-1] (ab93562)](https://www.abcam.com/ps/products/93/ab93562/Images/ab93562-108597-anti-cd19-antibody-mb19-1-phycoerythrin-flow-cytometry.jpg "Flow Cytometry - PE Anti-CD19 antibody [MB19-1] (ab93562)")
Key features and details
- PE Mouse monoclonal [MB19-1] to CD19
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgA
Related conjugates and formulations
Overview
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Product name
PE Anti-CD19 antibody [MB19-1]
See all CD19 primary antibodies -
Description
PE Mouse monoclonal [MB19-1] to CD19 -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to Mouse CD19. CD19+ Mouse pre-B cell line, 300.19
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Positive control
- BALB/c splenocytes and Mouse splenocytes
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 2.9% Sodium chloride, PBS -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
MB19-1 -
Isotype
IgA -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab93562 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
| Notes |
|---|
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. -
Involvement in disease
Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) [MIM:613493]; also called antibody deficiency due to CD19 defect. CVID3 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. -
Sequence similarities
Contains 2 Ig-like C2-type (immunoglobulin-like) domains. -
Post-translational
modificationsPhosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 12478 Mouse
- SwissProt: P25918 Mouse
- Unigene: 4360 Mouse
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Alternative names
- Antibody deficiency due to defect in CD19 antibody
- Antibody deficiency due to defect in CD19, included antibody
- AW495831 antibody
see all
Images
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Flow Cytometry - PE Anti-CD19 antibody [MB19-1] (ab93562)Staining of BALB/c splenocytes with staining buffer (autofluorescence) (open histogram) or ab93562 (colored histogram). Cells in the lymphocyte gate were used for analysis.
Datasheets and documents
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Datasheet download
References (0)
ab93562 has not yet been referenced specifically in any publications.
