PE Anti-CD1a antibody [NA1/34] (ab22352)
Key features and details
- PE Mouse monoclonal [NA1/34] to CD1a
- Suitable for: Flow Cyt
- Reacts with: Human, Cynomolgus monkey
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
Related conjugates and formulations
Overview
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Product name
PE Anti-CD1a antibody [NA1/34]
See all CD1a primary antibodies -
Description
PE Mouse monoclonal [NA1/34] to CD1a -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Specificity
ab222352 recognises specifically CD1a expressed by human cortical thymocytes, Langerhans cells, Dendritic cells and a subset of B cells. -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human, Cynomolgus monkey -
Immunogen
Tissue, cells or virus corresponding to Human CD1a. Fresh human thymocytes
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General notes
Recommended negative control: Mouse IgG2a Negative ControlThe Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
Purification notes
Purified IgG prepared by ion exchange chromatography -
Clonality
Monoclonal -
Clone number
NA1/34 -
Myeloma
NS1/1-Ag4-1 -
Isotype
IgG2a -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab22352 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Use 10µl for 106 cells.
ab91363 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. Use 10µl for 106 cells in 100µl. |
| Notes |
|---|
|
Flow Cyt
Use 10µl for 106 cells. ab91363 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. Use 10µl for 106 cells in 100µl. |
Target
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Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. -
Tissue specificity
Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. -
Sequence similarities
Contains 1 Ig-like (immunoglobulin-like) domain. -
Cellular localization
Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts. - Information by UniProt
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Database links
- Entrez Gene: 909 Human
- Omim: 188370 Human
- SwissProt: P06126 Human
- Unigene: 1309 Human
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Alternative names
- CD 1a antibody
- CD1 antibody
- CD1a antibody
see all
Datasheets and documents
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Datasheet download
References (2)
ab22352 has been referenced in 2 publications.
- de Jong MA et al. Mutz-3-derived Langerhans cells are a model to study HIV-1 transmission and potential inhibitors. J Leukoc Biol 87:637-43 (2010). PubMed: 20042470
- de Jong MA et al. Herpes simplex virus type 2 enhances HIV-1 susceptibility by affecting Langerhans cell function. J Immunol 185:1633-41 (2010). PubMed: 20592277
