PE Anti-CD200R antibody [OX102] (ab34135)
![Flow Cytometry - PE Anti-CD200R antibody [OX102] (ab34135)](https://www.abcam.com/ps/products/34/ab34135/Images/ab34135-47472-anti-cd200r-antibody-ox102-phycoerythrin-flow-cytometry.jpg "Flow Cytometry - PE Anti-CD200R antibody [OX102] (ab34135)")
Key features and details
- PE Mouse monoclonal [OX102] to CD200R
- Reacts with: Rat
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Overview
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Product name
PE Anti-CD200R antibody [OX102]
See all CD200R primary antibodies -
Description
PE Mouse monoclonal [OX102] to CD200R -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Specificity
This antibody is specific for the CD200R ligand. -
Species reactivity
Reacts with: Rat -
Immunogen
Tissue/ cell preparation: Membrane fraction of thioglycollate elicited rat peripheral cells.
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General notes
This antibody has been shown to block the interaction of OX2 ligand with CD200.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
Purity
Protein G purified -
Purification notes
This antibody was purified tissue culture supernatant. -
Primary antibody notes
This antibody has been shown to block the interaction of OX2 ligand with CD200. -
Clonality
Monoclonal -
Clone number
OX102 -
Myeloma
NS1 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Target
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Function
Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. -
Tissue specificity
Expressed in granulocytes, monocytes, most T cells, neutrophils, basophils and a subset of NK, NKT and B cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells. -
Sequence similarities
Belongs to the CD200R family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Post-translational
modificationsThe mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 64357 Rat
- SwissProt: Q9ES58 Rat
- Unigene: 124439 Rat
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Alternative names
- CD 200R antibody
- CD200 cell surface glycoprotein receptor antibody
- CD200 receptor 1 antibody
see all
Images
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Flow Cytometry - PE Anti-CD200R antibody [OX102] (ab34135)This image is courtesy of an Anonymous Abreview.Overlay histogram showing Rat blood cells stained with ab34135 (red line). The sample was prepared by lysing Red Blood cells and cells were fixed with formaldehyde. The cells were then incubated with the antibody for 1 hour diluted 1/100 in PBS/1% BSA/0.01% Azide. The cell population was gated on monocytes.
Datasheets and documents
References (1)
ab34135 has been referenced in 1 publication.
- Noh MY et al. Mesenchymal Stem Cells Modulate the Functional Properties of Microglia via TGF-ß Secretion. Stem Cells Transl Med 5:1538-1549 (2016). PubMed: 27400795
