PE Anti-CD200R antibody [OX108] (ab33366)

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Flow Cytometry - PE Anti-CD200R antibody [OX108] (ab33366)

    Key features and details

    • PE Mouse monoclonal [OX108] to CD200R
    • Suitable for: Flow Cyt
    • Reacts with: Human
    • Conjugation: PE. Ex: 488nm, Em: 575nm
    • Isotype: IgG1

    Overview

    • Product name

      PE Anti-CD200R antibody [OX108]
      See all CD200R primary antibodies

    • Description

      PE Mouse monoclonal [OX108] to CD200R

    • Host species

      Mouse

    • Conjugation

      PE. Ex: 488nm, Em: 575nm

    • Tested applications

      Suitable for: Flow Cytmore details

    • Species reactivity

      Reacts with: Human

    • Immunogen

      Fusion protein hCD200RCD4d3+4

    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    Applications

    Our Abpromise guarantee covers the use of ab33366 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt Use at an assay dependent concentration.

    Use neat - 1/10. Use 10ul working dilution to label 106 cells in 100ul

     

     

     

    ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

     

    Target

    • Function

      Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.

    • Tissue specificity

      Expressed in granulocytes, monocytes, most T cells, neutrophils, basophils and a subset of NK, NKT and B cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells.

    • Sequence similarities

      Belongs to the CD200R family.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    • Post-translational
      modifications

      The mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform.

    • Cellular localization

      Secreted and Cell membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • CD 200R antibody
        • CD200 cell surface glycoprotein receptor antibody
        • CD200 receptor 1 antibody
        • Cd200r1 antibody
        • Cell surface glycoprotein CD200 receptor 1 antibody
        • Cell surface glycoprotein OX2 receptor 1 antibody
        • Cell surface glycoprotein OX2 receptor antibody
        • cell surface glycoprotein receptor CD200 antibody
        • CRTR 2 antibody
        • CRTR2 antibody
        • HCRTR2 antibody
        • MO2R1_HUMAN antibody
        • MOX2 receptor antibody
        • MOX2R antibody
        • OX2R antibody
        see all

      Images

      • Flow Cytometry - PE Anti-CD200R antibody [OX108] (ab33366)
        Flow Cytometry - PE Anti-CD200R antibody [OX108] (ab33366)
        Staining of human peripheral blood lymphocytes with ab33366

      References (1)

      Publishing research using ab33366? Please let us know so that we can cite the reference in this datasheet.

      ab33366 has been referenced in 1 publication.

      • Li W  et al. Haemophilus ducreyi-induced interleukin-10 promotes a mixed M1 and M2 activation program in human macrophages. Infect Immun 80:4426-34 (2012). Human . PubMed: 23027536

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