PE Anti-CD28 antibody [E18] (ab64638)

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Key features and details

  • PE Mouse monoclonal [E18] to CD28
  • Reacts with: Mouse
  • Conjugation: PE. Ex: 488nm, Em: 575nm
  • Isotype: IgG2b

Overview

  • Product name

    PE Anti-CD28 antibody [E18]
    See all CD28 primary antibodies

  • Description

    PE Mouse monoclonal [E18] to CD28

  • Host species

    Mouse

  • Conjugation

    PE. Ex: 488nm, Em: 575nm

  • Specificity

    ab64638 recognises murine CD28, a co-stimulatory cell surface molecule expressed by T cell subsets. Clone E18 has been shown to be able to stimulate murine T lymphocytes in combination with anti-mouse CD3.

  • Species reactivity

    Reacts with: Mouse

  • Immunogen

    Alternate immunisation with A20 cells expressing mCD28 and recombinant mCD28Ig.

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

Applications

  • Application notes
    Flow Cyt: neat - 1/10. Use 10ul of the suggested working dilution to label 106 cells in 100ul.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • Function

      Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.

    • Tissue specificity

      Expressed in T-cells and plasma cells, but not in less mature B-cells.

    • Sequence similarities

      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    • Cellular localization

      Membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • CD 28 antibody
        • CD28 antibody
        • CD28 antigen antibody
        • CD28 molecule antibody
        • CD28_HUMAN antibody
        • MGC138290 antibody
        • T cell antigen CD28 antibody
        • T cell specific surface glycoprotein antibody
        • T cell specific surface glycoprotein CD28 antibody
        • T-cell-specific surface glycoprotein CD28 antibody
        • TP44 antibody
        see all

      References (0)

      Publishing research using ab64638? Please let us know so that we can cite the reference in this datasheet.

      ab64638 has not yet been referenced specifically in any publications.

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