PE Anti-CD39 antibody [A1] (ab30424)

Submit a review Submit a question References (3)

Key features and details

  • PE Mouse monoclonal [A1] to CD39
  • Reacts with: Human
  • Conjugation: PE. Ex: 488nm, Em: 575nm
  • Isotype: IgG1

Overview

  • Product name

    PE Anti-CD39 antibody [A1]
    See all CD39 primary antibodies

  • Description

    PE Mouse monoclonal [A1] to CD39

  • Host species

    Mouse

  • Conjugation

    PE. Ex: 488nm, Em: 575nm

  • Specificity

    Binds to the human CD39 cell surface antigen (70-100kD)

  • Species reactivity

    Reacts with: Human

  • Immunogen

    PHA activated human lymphocytes.

  • General notes


    CD39 has intrinsic ecto-ATPase activity.

    Purified IgG conjugated to R. Phycoerythrin (RPE).

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C.

  • Storage buffer

    pH: 7.40
    Preservative: 0.09% Sodium azide
    Constituents: PBS, 1% BSA
  • Concentration information loading...

  • Purity

    Protein G purified

  • Purification notes

    Protein G affinity chromatography from tissue culture supernatant.

  • Primary antibody notes

    CD39 has intrinsic ecto-ATPase activity.

  • Clonality

    Monoclonal

  • Clone number

    A1

  • Myeloma

    NS1

  • Isotype

    IgG1

  • Research areas

Target

  • Function

    In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well.

  • Tissue specificity

    Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only.

  • Sequence similarities

    Belongs to the GDA1/CD39 NTPase family.

  • Post-translational
    modifications

    The N-terminus is blocked.
    Palmitoylated in the N-terminal part.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Database links

    • Form

      There are 3 isoforms produced by alternative splicing.

    • Alternative names

      • ATPDase antibody
      • CD 39 antibody
      • CD39 antibody
      • CD39 antigen antibody
      • DKFZp686D194 antibody
      • DKFZp686I093 antibody
      • Ecto apyrase antibody
      • Ecto ATP diphosphohydrolase antibody
      • Ecto-apyrase antibody
      • Ecto-ATP diphosphohydrolase 1 antibody
      • Ecto-ATPase 1 antibody
      • Ecto-ATPDase 1 antibody
      • Ectonucleoside triphosphate diphosphohydrolase 1 antibody
      • ENTP1_HUMAN antibody
      • ENTPD 1 antibody
      • ENTPD1 antibody
      • FLJ40921 antibody
      • FLJ40959 antibody
      • Lymphoid cell activation antigen antibody
      • NTPDase 1 antibody
      • NTPDase1 antibody
      • SPG64 antibody
      see all

    References (3)

    Publishing research using ab30424? Please let us know so that we can cite the reference in this datasheet.

    ab30424 has been referenced in 3 publications.

    • Jandus C  et al. Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides. Arthritis Rheum 58:2307-17 (2008). Flow Cyt ; Human . PubMed: 18668556
    • Valencic E  et al. T cells stimulated in vitro have a suppressive function but do not contain only regulatory T cells. Clin Exp Immunol 150:561-6 (2007). Flow Cyt ; Human . PubMed: 17900303
    • Aversa GG  et al. Detection of a late lymphocyte activation marker by A1, a new monoclonal antibody. Transplant Proc 20:49-52 (1988). PubMed: 2830689

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab30424.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com