PE Anti-CD42b antibody [HIP1] (ab90951)
![Flow Cytometry - PE Anti-CD42b antibody [HIP1] (ab90951)](https://www.abcam.com/ps/products/90/ab90951/Images/CD42b-Primary-antibodies-ab90951-4.jpg "Flow Cytometry - PE Anti-CD42b antibody [HIP1] (ab90951)")
Key features and details
- PE Mouse monoclonal [HIP1] to CD42b
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Overview
-
Product name
PE Anti-CD42b antibody [HIP1]
See all CD42b primary antibodies -
Description
PE Mouse monoclonal [HIP1] to CD42b -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Human peripherial blood mononuclear cells of a patient suffering with CLL.
-
Positive control
- Human peripheral blood platelets.
-
General notes
Clone HIP1 antibody inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets, ristocetin-induced platelet agglutination and partially inhibits collagen induced aggregation.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: 1% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Primary antibody notes
Clone HIP1 antibody inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets, ristocetin-induced platelet agglutination and partially inhibits collagen induced aggregation. -
Clonality
Monoclonal -
Clone number
HIP1 -
Isotype
IgG1 -
Research areas
Associated products
-
Alternative Versions
-
Isotype control
-
Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab90951 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use 20µl for 106 cells. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
Target
-
Relevance
CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF. -
Cellular localization
Cell Membrane -
Database links
- Entrez Gene: 2811 Human
- Omim: 606672 Human
- SwissProt: P07359 Human
- Unigene: 1472 Human
-
Alternative names
- Antigen CD42b alpha antibody
- BDPLT1 antibody
- BDPLT3 antibody
see all
Images
-
Flow Cytometry - PE Anti-CD42b antibody [HIP1] (ab90951)ab90951, at 20µl/106 cells, staining CD42b in Human platelets from normal peripheral blood by Flow Cytometry.
-
![Flow Cytometry - PE Anti-CD42b antibody [HIP1] (ab90951)](https://www.abcam.com/ps/products/90/ab90951/Images/CD42b-Primary-antibodies-ab90951-3.jpg)
Flow Cytometry - PE Anti-CD42b antibody [HIP1] (ab90951)ab90951, at 20µl/106 cells, staining CD42b in Human Platelets from normal peripheral blood by Flow Cytometry.
Datasheets and documents
References (2)
ab90951 has been referenced in 2 publications.
- Di Buduo CA et al. Modular flow chamber for engineering bone marrow architecture and function. Biomaterials 146:60-71 (2017). PubMed: 28898758
- Di Buduo CA et al. Abnormal proplatelet formation and emperipolesis in cultured human megakaryocytes from gray platelet syndrome patients. Sci Rep 6:23213 (2016). PubMed: 26987485
