PE Anti-CD90 / Thy1 antibody [MRC OX-7] (ab33694)
Key features and details
- PE Mouse monoclonal [MRC OX-7] to CD90 / Thy1
- Suitable for: Flow Cyt
- Reacts with: Mouse, Rat
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
Overview
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Product name
PE Anti-CD90 / Thy1 antibody [MRC OX-7]
See all CD90 / Thy1 primary antibodies -
Description
PE Mouse monoclonal [MRC OX-7] to CD90 / Thy1 -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Specificity
Since CD90 is a monomorphic determinant in rat but polymorphic in mice, clone MRC OX-7 reacts with Thy1.1 mice e.g. AKR and FVB mice, but not Thy1.2 mice such as CBA and BALB/c. The affinity of the Fab' of MRC OX-7 for rat Thy1 is 3 x 109m-1 and for mouse Thy1.1 is 3 x 108m-1 -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse, Rat -
Immunogen
Full length protein corresponding to CD90/ Thy1. Rat CD90 antigen.
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Positive control
- Rat and mouse CD90 is expressed on a variety of cell types including thymocytes, neuronal cells, stem cells, T lymphocytes (mouse), immature B cells (rat) and connective tissues.
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General notes
ab33694 has been demonstrated to promote neurite outgrowths on peripherin-stained sympathetic rat neurons, using fluorescence microscopy.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
Purity
Protein G purified -
Primary antibody notes
ab33694 has been demonstrated to promote neurite outgrowths on peripherin-stained sympathetic rat neurons, using fluorescence microscopy. -
Clonality
Monoclonal -
Clone number
MRC OX-7 -
Myeloma
NS1 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
- HRP Anti-CD90 / Thy1 antibody [MRC OX-7] (ab199219)
- PerCP Anti-CD90 / Thy1 antibody [MRC OX-7] (ab216354)
- Anti-CD90 / Thy1 antibody [MRC OX-7] - BSA and Azide free (ab222781)
- Anti-CD90 / Thy1 antibody [MRC OX-7] - Hematopoietic Stem Cell Marker (ab225)
- FITC Anti-CD90 / Thy1 antibody [MRC OX-7] (ab226)
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab33694 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
or 100ul whole blood. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| Notes |
|---|
|
Flow Cyt
Use at an assay dependent concentration. or 100ul whole blood. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Target
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Function
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. -
Sequence similarities
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 21838 Mouse
- Entrez Gene: 24832 Rat
- SwissProt: P01831 Mouse
- SwissProt: P01830 Rat
- Unigene: 3951 Mouse
- Unigene: 108198 Rat
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Alternative names
- CD7 antibody
- CD90 antibody
- CD90 antigen antibody
see all
Datasheets and documents
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Datasheet download
References (10)
ab33694 has been referenced in 10 publications.
- Oh J et al. Mesenchymal stem cells genetically engineered to express platelet-derived growth factor and heme oxygenase-1 ameliorate osteoarthritis in a canine model. J Orthop Surg Res 16:43 (2021). PubMed: 33430899
- Zhao B et al. Transplantation of bone marrow-derived mesenchymal stem cells with silencing of microRNA-138 relieves pelvic organ prolapse through the FBLN5/IL-1ß/elastin pathway. Aging (Albany NY) 13:3045-3059 (2021). PubMed: 33460398
- Lin Y et al. In vitro behavior of tendon stem/progenitor cells on bioactive electrospun nanofiber membranes for tendon-bone tissue engineering applications. Int J Nanomedicine 14:5831-5848 (2019). PubMed: 31534327
- Lam PK et al. Topical Application of Mesenchymal Stromal Cells Ameliorated Liver Parenchyma Damage After Ischemia-Reperfusion Injury in an Animal Model. Transplant Direct 3:e160 (2017). Flow Cyt ; Rat . PubMed: 28620644
- Sun W et al. Proanthocyanidins Attenuation of H2O2-Induced Oxidative Damage in Tendon-Derived Stem Cells via Upregulating Nrf-2 Signaling Pathway. Biomed Res Int 2017:7529104 (2017). PubMed: 29201913
- Liu X et al. Mechanical Tension Promotes the Osteogenic Differentiation of Rat Tendon-derived Stem Cells Through the Wnt5a/Wnt5b/JNK Signaling Pathway. Cell Physiol Biochem 36:517-30 (2015). PubMed: 25966835
- Zhang J et al. Adenovirus-mediated delivery of the human IFN-? gene potentiates the cytotoxicity of daunorubicin against leukemic cells through downregulation of the a4ß1 integrin/ILK/apoptosis pathway. Oncol Lett 7:361-368 (2014). Flow Cyt ; Human . PubMed: 24396448
- Rui YF et al. Altered fate of tendon-derived stem cells isolated from a failed tendon-healing animal model of tendinopathy. Stem Cells Dev 22:1076-85 (2013). Flow Cyt ; Rat . PubMed: 23106341
- Das A et al. The promotion of mandibular defect healing by the targeting of S1P receptors and the recruitment of alternatively activated macrophages. Biomaterials 34:9853-62 (2013). PubMed: 24064148
- Tan Q et al. Effect of In Vitro Passaging on the Stem Cell-Related Properties of Tendon-Derived Stem Cells-Implications in Tissue Engineering. Stem Cells Dev : (2011). Flow Cyt ; Rat . PubMed: 21627568
