PE Anti-CSF-1-R antibody [12-3A3-1B10] (ab95731)
![Flow Cytometry - PE Anti-CSF-1-R antibody [12-3A3-1B10] (ab95731)](https://www.abcam.com/ps/products/95/ab95731/Images/ab95731-109982-anti-mcsf-receptor-antibody-12-3a3-1b10-phycoerythrin-flow-cytometry.jpg "Flow Cytometry - PE Anti-CSF-1-R antibody [12-3A3-1B10] (ab95731)")
Key features and details
- PE Rat monoclonal [12-3A3-1B10] to CSF-1-R
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
Overview
-
Product name
PE Anti-CSF-1-R antibody [12-3A3-1B10]
See all CSF-1-R primary antibodies -
Description
PE Rat monoclonal [12-3A3-1B10] to CSF-1-R -
Host species
Rat -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus corresponding to Human CSF-1-R. Helper free retrovirus containing human c-fms gene.
-
Positive control
- Flow Cyt: Normal human peripheral blood cells.
-
General notes
Excitation: 488 nm Emission: 575 nm.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.2% BSA, 0.87% Sodium chloride, PBS -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
12-3A3-1B10 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
-
Alternative Versions
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab95731 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Use 5µl for 106 cells.
ab154449 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| Notes |
|---|
|
Flow Cyt
Use 5µl for 106 cells. ab154449 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Target
-
Function
Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34. -
Tissue specificity
Expressed in bone marrow and in differentiated blood mononuclear cells. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 1436 Human
- Omim: 164770 Human
- SwissProt: P07333 Human
- Unigene: 586219 Human
-
Alternative names
- C FMS antibody
- CD 115 antibody
- CD115 antibody
see all
Images
-
Flow Cytometry - PE Anti-CSF-1-R antibody [12-3A3-1B10] (ab95731)
Staining of normal human peripheral blood cells with Isotype Contol (open histogram) or ab95731 (filled histogram).
Datasheets and documents
-
Datasheet download
References (1)
ab95731 has been referenced in 1 publication.
- Kumar J et al. Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer. Br J Cancer 110:133-45 (2014). Flow Cyt ; Human . PubMed: 24220695
