PE Anti-DR3/LARD antibody [JD3] (ab234231)
![Flow Cytometry - PE Anti-DR3/LARD antibody [JD3] (ab234231)](https://www.abcam.com/ps/products/234/ab234231/Images/ab234231-308308-anti-dr3-antibody-jd3-phycoerythrin-flow-cytometry.jpg "Flow Cytometry - PE Anti-DR3/LARD antibody [JD3] (ab234231)")
Key features and details
- PE Mouse monoclonal [JD3] to DR3/LARD
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Overview
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Product name
PE Anti-DR3/LARD antibody [JD3]
See all DR3/LARD primary antibodies -
Description
PE Mouse monoclonal [JD3] to DR3/LARD -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Fusion protein corresponding to DR3/LARD. (Human DR3/LARD-Ig fusion protein).
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Positive control
- Flow Cytometry: DR3/LARD-transfected HEK-293 cells.
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General notes
This product was previously labelled as DR3
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.0975% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Size exclusion -
Purification notes
ab234231 is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. -
Clonality
Monoclonal -
Clone number
JD3 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab234231 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use 10µl for 106 cells. |
Target
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Function
Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. -
Tissue specificity
Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate. -
Sequence similarities
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 8718 Human
- Omim: 603366 Human
- SwissProt: Q93038 Human
- Unigene: 462529 Human
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Alternative names
- Apo 3 antibody
- Apo-3 antibody
- Apo3 antibody
see all
Images
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Flow Cytometry - PE Anti-DR3/LARD antibody [JD3] (ab234231)
Flow Cytometry analysis of DR3/LARD-transfected (red) and non-transfected HEK-293 (human epithelial cell line from embryonic kidney) (black) cells labeling DR3/LARD with ab234231. Surface staining.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab234231 has not yet been referenced specifically in any publications.
