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  1. Link

    pe-hla-class-i-antibody-mem-147-ab52451.pdf

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Immunology Adaptive Immunity MHC Class I
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PE Anti-HLA Class I antibody [MEM-147] (ab52451)

  • Datasheet
  • SDS
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Key features and details

  • PE Mouse monoclonal [MEM-147] to HLA Class I
  • Reacts with: Human
  • Conjugation: PE. Ex: 488nm, Em: 575nm
  • Isotype: IgG1

Overview

  • Product name

    PE Anti-HLA Class I antibody [MEM-147]
    See all HLA Class I primary antibodies
  • Description

    PE Mouse monoclonal [MEM-147] to HLA Class I
  • Host species

    Mouse
  • Conjugation

    PE. Ex: 488nm, Em: 575nm
  • Specificity

    ab5451 recognises all human classical MHC Class I molecules in native cell-surface forms (e.g. it recognizes native HLA-A2 in cytofluorometry and immunoprecipitation but not in Western blotting). MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. ab52451 is positive in Western blotting (non-reducing conditions) only with most HLA-B and HLA-C molecules, but not HLA-A.
  • Species reactivity

    Reacts with: Human
  • Immunogen

    PHA-activated peripheral blood lymphocytes.

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    pH: 7.4
    Preservative: 0.097% Sodium azide
    Constituent: 0.2% BSA

    BSA (high-grade protease free),
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    ab52451 was purified by Protein G prior to conjugation. After conjugation, it was purified by site exclusion chromatography. Purity >95% by SDS-PAGE.
  • Clonality

    Monoclonal
  • Clone number

    MEM-147
  • Isotype

    IgG1
  • Research areas

    • Immunology
    • Adaptive Immunity
    • MHC
    • Class I

Associated products

  • Alternative Versions

    • Anti-HLA Class I antibody [MEM-147] (ab9090)
  • Isotype control

    • PE Mouse IgG1 [B11/6] - Isotype Control (ab91357)

Target

  • Relevance

    HLA CLass I is involved in the presentation of foreign antigens to the immune system.
  • Cellular localization

    Plasma membrane
  • Database links

    • Entrez Gene: 3105 Human
    • Entrez Gene: 3133 Human
    • Entrez Gene: 3134 Human
    • Entrez Gene: 3135 Human
    • Omim: 142800 Human
    • SwissProt: O15506 Human
    • SwissProt: P01891 Human
    • SwissProt: P01892 Human
    • SwissProt: P04439 Human
    • SwissProt: P05534 Human
    • SwissProt: P10314 Human
    • SwissProt: P13746 Human
    • SwissProt: P16188 Human
    • SwissProt: P16189 Human
    • SwissProt: P16190 Human
    • SwissProt: P18462 Human
    • SwissProt: P30443 Human
    • SwissProt: P30447 Human
    • SwissProt: P30450 Human
    • SwissProt: P30453 Human
    • SwissProt: P30455 Human
    • SwissProt: P30456 Human
    • SwissProt: P30457 Human
    • SwissProt: P30459 Human
    • SwissProt: P30512 Human
    • SwissProt: Q09160 Human
    • SwissProt: Q5MCQ6 Human
    • SwissProt: Q5ZGM8 Human
    • SwissProt: Q7YQ33 Human
    • SwissProt: Q861B7 Human
    • SwissProt: Q8MHP7 Human
    • SwissProt: Q9MY64 Human
    • SwissProt: Q9MY72 Human
    • SwissProt: Q9MYB7 Human
    • Unigene: 549038 Human
    see all
  • Alternative names

    • DKFZp686P19218 antibody
    • EA1.2 antibody
    • EA2.1 antibody
    • HLA 5.4 antibody
    • HLA 6.2 antibody
    • HLA A antibody
    • HLA B antibody
    • HLA C antibody
    • HLA CDA12 antibody
    • HLA F antibody
    • HLA G antibody
    • HLA G histocompatibility antigen class I G antibody
    • HLAF antibody
    • Major histocompatibility complex class I A antibody
    • Major histocompatibility complex class I antibody
    • Major histocompatibility complex class I E antibody
    • Major histocompatibility complex class I F antibody
    • MHC antibody
    • MHC Class I antigen antibody
    • MHC G antibody
    see all

Protocols

  • Flow cytometry protocols

Click here to view the general protocols

Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab52451? Please let us know so that we can cite the reference in this datasheet.

    ab52451 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    There are currently no Customer reviews or Questions for ab52451.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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