Key features and details
- PE Rat monoclonal [7D4] to IL-2 Receptor alpha
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgM
Product namePE Anti-IL-2 Receptor alpha antibody [7D4]
See all IL-2 Receptor alpha primary antibodies
DescriptionPE Rat monoclonal [7D4] to IL-2 Receptor alpha
ConjugationPE. Ex: 488nm, Em: 575nm
SpecificityThis antibody recognises low affinity IL-2 receptor alpha.
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Mouse
Tissue, cells or virus corresponding to Mouse IL-2 Receptor alpha.
EpitopeThis antibody reacts with an epitope located between amino acids 125 and 212 of IL-2 receptor alpha.
- Cells from BALB/c spleen activated with PMA and ionomycin for Immunofluorescent staining with Flow Cytometric analysis.
This antibody does not block the binding of IL-2 to CD25.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.3
Preservative: 0.09% Sodium azide
Constituents: PBS, 16% Sucrose
Concentration information loading...
Primary antibody notesThis antibody does not block the binding of IL2 to CD25.
Light chain typekappa
Our Abpromise guarantee covers the use of ab24933 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 0.2µg for 106 cells.
ab154451 - Rat monoclonal IgM, is suitable for use as an isotype control with this antibody.
FunctionReceptor for interleukin-2.
Involvement in diseaseGenetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Sequence similaritiesContains 2 Sushi (CCP/SCR) domains.
- Information by UniProt
- Interleukin 2 receptor alpha chain antibody
- CD25 antibody
- CD25 antigen antibody
ab24933 has not yet been referenced specifically in any publications.