Key features and details
- PE Mouse monoclonal [NGFR5] to p75 NGF Receptor, prediluted
- Reacts with: Rabbit, Cat, Human, Ferret, Non human primates
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Product namePE Anti-p75 NGF Receptor antibody [NGFR5], prediluted
See all p75 NGF Receptor primary antibodies
DescriptionPE Mouse monoclonal [NGFR5] to p75 NGF Receptor, prediluted
ConjugationPE. Ex: 488nm, Em: 575nm
Species reactivityReacts with: Rabbit, Cat, Human, Ferret, Non human primates
Does not react with: Mouse, Rat
Purified p75 NGF Receptor protein isolated from Human melanoma cell line A875.
EpitopeThe epitope is localized within amino acids 1-160.
- Human blood cells.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 0.2% BSA, 99% PBS
Concentration information loading...
- APC Anti-p75 NGF Receptor antibody [NGFR5], prediluted (ab176522)
- Anti-p75 NGF Receptor antibody [NGFR5] - BSA and Azide free (ab212682)
- PE/Cy7® Anti-p75 NGF Receptor antibody [NGFR5] (ab234270)
- PerCP/Cy5.5® Anti-p75 NGF Receptor antibody [NGFR5] (ab234446)
- Anti-p75 NGF Receptor antibody [NGFR5] (ab3125)
FunctionLow affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.
Sequence similaritiesContains 1 death domain.
Contains 4 TNFR-Cys repeats.
DomainDeath domain is responsible for interaction with RANBP9.
The extracellular domain is responsible for interaction with NTRK1.
modificationsN- and O-glycosylated.
O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc.
Phosphorylated on serine residues.
- Information by UniProt
- CD271 antibody
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ab157333 has been referenced in 1 publication.
- Zhao F et al. Programmed cell death 1 correlates with the occurrence and development of MG63 osteosarcoma. Oncol Lett 12:5199-5204 (2016). Flow Cyt ; Human . PubMed: 28105229