PE Anti-p75 NGF Receptor antibody [NGFR5], prediluted (ab157333)
Key features and details
- PE Mouse monoclonal [NGFR5] to p75 NGF Receptor, prediluted
- Reacts with: Rabbit, Cat, Human, Ferret, Non human primates
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Overview
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Product name
PE Anti-p75 NGF Receptor antibody [NGFR5], prediluted
See all p75 NGF Receptor primary antibodies -
Description
PE Mouse monoclonal [NGFR5] to p75 NGF Receptor, prediluted -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Species reactivity
Reacts with: Rabbit, Cat, Human, Ferret, Non human primates
Does not react with: Mouse, Rat -
Immunogen
Purified p75 NGF Receptor protein isolated from Human melanoma cell line A875.
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Epitope
The epitope is localized within amino acids 1-160. -
Positive control
- Human blood cells.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 0.2% BSA, 99% PBS -
Concentration information loading... -
Purity
Size exclusion -
Clonality
Monoclonal -
Clone number
NGFR5 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
- APC Anti-p75 NGF Receptor antibody [NGFR5], prediluted (ab176522)
- Anti-p75 NGF Receptor antibody [NGFR5] - BSA and Azide free (ab212682)
- PE/Cy7® Anti-p75 NGF Receptor antibody [NGFR5] (ab234270)
- PerCP/Cy5.5® Anti-p75 NGF Receptor antibody [NGFR5] (ab234446)
- Anti-p75 NGF Receptor antibody [NGFR5] (ab3125)
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Isotype control
Target
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Function
Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. -
Sequence similarities
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
Domain
Death domain is responsible for interaction with RANBP9.
The extracellular domain is responsible for interaction with NTRK1. -
Post-translational
modificationsN- and O-glycosylated.
O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc.
Phosphorylated on serine residues. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 101101519 Cat
- Entrez Gene: 101680416 Ferret
- Entrez Gene: 4804 Human
- Entrez Gene: 100349095 Rabbit
- Omim: 162010 Human
- SwissProt: P08138 Human
- Unigene: 415768 Human
- Unigene: 681726 Human
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Alternative names
- CD271 antibody
- CD271 antigen antibody
- Gp80 LNGFR antibody
see all
References (1)
ab157333 has been referenced in 1 publication.
- Zhao F et al. Programmed cell death 1 correlates with the occurrence and development of MG63 osteosarcoma. Oncol Lett 12:5199-5204 (2016). Flow Cyt ; Human . PubMed: 28105229
