Key features and details
- PE Rat monoclonal [TY25] to PD-L2
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
Product namePE Anti-PD-L2 antibody [TY25]
See all PD-L2 primary antibodies
DescriptionPE Rat monoclonal [TY25] to PD-L2
ConjugationPE. Ex: 488nm, Em: 575nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Mouse
Tissue, cells or virus corresponding to Mouse PD-L2. Mouse PD-L2 transfected cell line.
Database link: Q9BQ51
- Mouse splenocyte suspensions and PD-L2 transfected cells
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS
Concentration information loading...
PurityProtein G purified
Light chain typekappa
Our Abpromise guarantee covers the use of ab93589 in the following tested applications.
|Flow Cyt||Use 0.06-0.5µg for 105-8 cells.|
FunctionInvolved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Tissue specificityHighly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Sequence similaritiesBelongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Cellular localizationSecreted; Cell membrane and Endomembrane system.
- Information by UniProt
- B7 dendritic cell molecule antibody
- B7-DC antibody
- B7DC antibody
ab93589 has been referenced in 4 publications.
- Tanaka K et al. PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection. J Immunol 179:5204-10 (2007). PubMed: 17911605
- Kanai T et al. Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. J Immunol 171:4156-63 (2003). PubMed: 14530338
- Ansari MJ et al. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med 198:63-9 (2003). PubMed: 12847137
- Yamazaki T et al. Expression of programmed death 1 ligands by murine T cells and APC. J Immunol 169:5538-45 (2002). PubMed: 12421930