PE Anti-Sialoadhesin/CD169 antibody [7-239], prediluted (ab200579)
Key features and details
- PE Mouse monoclonal [7-239] to Sialoadhesin/CD169, prediluted
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Overview
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Product name
PE Anti-Sialoadhesin/CD169 antibody [7-239], prediluted
See all Sialoadhesin/CD169 primary antibodies -
Description
PE Mouse monoclonal [7-239] to Sialoadhesin/CD169, prediluted -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus corresponding to Human Sialoadhesin/CD169. Human rhinovirus 14-infected monocyte-derived dendritic cells.
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Positive control
- Human blood and blood cells.
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General notes
This product was previously labelled as Sialoadhesin
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Avoid freeze / thaw cycle. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.098% Sodium azide
Constituents: 99% PBS, 0.2% BSA
High grade protease free BSA -
Concentration information loading... -
Purity
Size exclusion -
Purification notes
ab200579 is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. -
Clonality
Monoclonal -
Clone number
7-239 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
Target
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Function
Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis. -
Tissue specificity
Expressed by macrophages in various tissues. High levels are found in spleen, lymph node, perivascular macrophages in brain and lower levels in bone marrow, liver Kupffer cells and lamina propria of colon and lung. Also expressed by inflammatory macrophages in rheumatoid arthritis. -
Sequence similarities
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Contains 16 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 6614 Human
- Omim: 600751 Human
- SwissProt: Q9BZZ2 Human
- Unigene: 31869 Human
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Alternative names
- CD169 antibody
- CD169 antigen antibody
- dJ1009E24.1 antibody
see all
Datasheets and documents
References (0)
ab200579 has not yet been referenced specifically in any publications.
