PE Anti-uPA Receptor/U-PAR antibody [VIM5] (ab232917)
![Flow Cytometry - PE Anti-uPA Receptor/U-PAR antibody [VIM5] (ab232917)](https://www.abcam.com/ps/products/232/ab232917/Images/ab232917-304543-2329171.jpg "Flow Cytometry - PE Anti-uPA Receptor/U-PAR antibody [VIM5] (ab232917)")
Key features and details
- PE Mouse monoclonal [VIM5] to uPA Receptor/U-PAR
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Overview
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Product name
PE Anti-uPA Receptor/U-PAR antibody [VIM5]
See all uPA Receptor/U-PAR primary antibodies -
Description
PE Mouse monoclonal [VIM5] to uPA Receptor/U-PAR -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus corresponding to uPA Receptor/U-PAR. THP-1 (Human monocytic leukemia cell line) cells.
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Positive control
- Flow Cytometry: Human peripheral blood cells.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.0975% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Size exclusion -
Clonality
Monoclonal -
Clone number
VIM5 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab232917 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use 20µl for 106 cells. |
Target
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Function
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. -
Tissue specificity
Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. -
Sequence similarities
Contains 3 UPAR/Ly6 domains. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 5329 Human
- Omim: 173391 Human
- SwissProt: Q03405 Human
- Unigene: 466871 Human
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Alternative names
- CD 87 antibody
- CD87 antibody
- CD87 antigen antibody
see all
Images
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Flow Cytometry - PE Anti-uPA Receptor/U-PAR antibody [VIM5] (ab232917)
Surface staining of human peripheral blood cells labeling uPA Receptor/U-PAR with ab232917 (10 μl reagent / 100 μl of whole blood). Gating strategy - leukocyte gate.
Recommended negative control: ab125926.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab232917 has not yet been referenced specifically in any publications.
