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  1. Link

    pecy5-tcr-alpha--tcr-beta-antibody-ip26-ab95645.pdf

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Immunology Adaptive Immunity T Cells Non-CD
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PE/Cy5® Anti-TCR alpha + TCR beta antibody [IP26] (ab95645)

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Key features and details

  • PE/Cy5® Mouse monoclonal [IP26] to TCR alpha + TCR beta
  • Reacts with: Human
  • Conjugation: PE/Cy5®. Ex: 496nm, Em: 670nm
  • Isotype: IgG1

Overview

  • Product name

    PE/Cy5® Anti-TCR alpha + TCR beta antibody [IP26]
    See all TCR alpha + TCR beta primary antibodies
  • Description

    PE/Cy5® Mouse monoclonal [IP26] to TCR alpha + TCR beta
  • Host species

    Mouse
  • Conjugation

    PE/Cy5®. Ex: 496nm, Em: 670nm
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Human TCR alpha + TCR beta

  • Positive control

    • Human peripheral blood leukocytes
  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    pH: 7.20
    Preservative: 0.09% Sodium azide
    Constituents: 0.2% BSA, 0.87% Sodium chloride, PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Clonality

    Monoclonal
  • Clone number

    IP26
  • Isotype

    IgG1
  • Light chain type

    kappa
  • Research areas

    • Immunology
    • Adaptive Immunity
    • T Cells
    • Non-CD

Associated products

  • Alternative Versions

    • Biotin Anti-TCR alpha + TCR beta antibody [IP26] (ab95647)
    • FITC Anti-TCR alpha + TCR beta antibody [IP26] (ab95648)
    • PE Anti-TCR alpha + TCR beta antibody [IP26] (ab99857)
    • APC Anti-TCR alpha + TCR beta antibody [IP26] (ab99859)
  • Isotype control

    • PE/Cy5® Mouse IgG1, kappa monoclonal [15H6] - Isotype control (ab67435)

Target

  • Relevance

    The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
  • Cellular localization

    Type I membrane protein.
  • Database links

    • Entrez Gene: 6955 Human
    • Entrez Gene: 6957 Human
    • Omim: 186880 Human
    • Omim: 186930 Human
    • SwissProt: P01848 Human
    • SwissProt: P04435 Human
    • Unigene: 494963 Human
    • Alternative names

      • FLJ22602 antibody
      • MGC117436 antibody
      • MGC22624 antibody
      • MGC23964 antibody
      • MGC71411 antibody
      • T cell antigen receptor alpha polypeptide antibody
      • T cell antigen receptor beta polypeptide T cell receptor beta cluster antibody
      • T cell receptor alpha (V D J C) antibody
      • T cell receptor alpha chain C region antibody
      • T cell receptor alpha constant antibody
      • T cell receptor alpha locus antibody
      • T cell receptor beta cluster antibody
      • T cell receptor beta locus antibody
      • TCRA antibody
      • TCRB antibody
      • TCRD antibody
      • TRA antibody
      • TRAC antibody
      • TRB antibody
      see all

    Protocols

    • Flow cytometry protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab95645? Please let us know so that we can cite the reference in this datasheet.

    ab95645 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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