PE/Cy7® Anti-CD11c antibody [N418] (ab210310)

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Flow Cytometry - PE/Cy7® Anti-CD11c antibody [N418] (ab210310)

    Key features and details

    • PE/Cy7® Armenian hamster monoclonal [N418] to CD11c
    • Suitable for: Flow Cyt
    • Reacts with: Mouse
    • Conjugation: PE/Cy7®. Ex: 496nm, Em: 774nm
    • Isotype: IgG

    Overview

    • Product name

      PE/Cy7® Anti-CD11c antibody [N418]
      See all CD11c primary antibodies

    • Description

      PE/Cy7® Armenian hamster monoclonal [N418] to CD11c

    • Host species

      Armenian hamster

    • Conjugation

      PE/Cy7®. Ex: 496nm, Em: 774nm

    • Tested applications

      Suitable for: Flow Cytmore details

    • Species reactivity

      Reacts with: Mouse

    • Positive control

      • C57Bl/6 splenocytes.

    • General notes

      This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    Applications

    Our Abpromise guarantee covers the use of ab210310 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt Use at an assay dependent concentration.

    Suggested use 1 μg.

    Target

    • Function

      Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

    • Tissue specificity

      Predominantly expressed in monocytes and granulocytes.

    • Sequence similarities

      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.

    • Domain

      The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.

    • Cellular localization

      Membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • 95 alpha chain antibody
        • 95 antibody
        • CD 11c antibody
        • CD11 antigen like family member C antibody
        • CD11 antigen-like family member C antibody
        • CD11c antibody
        • CD11c antigen antibody
        • Complement component 3 receptor 4 subunit antibody
        • CR4 antibody
        • Integrin alpha X antibody
        • Integrin alpha X chain antibody
        • Integrin alpha-X antibody
        • Integrin aX antibody
        • Integrin subunit alpha X antibody
        • integrin, alpha X (antigen CD11C (p150), alpha polypeptide) antibody
        • integrin, alpha X (complement component 3 receptor 4 subunit antibody
        • ITAX_HUMAN antibody
        • ITGAX antibody
        • LEU M5 alpha subunit antibody
        • Leu M5 antibody
        • Leukocyte adhesion glycoprotein p150 95 alpha chain antibody
        • Leukocyte adhesion glycoprotein p150 antibody
        • Leukocyte adhesion receptor p150 95 antibody
        • Leukocyte adhesion receptor p150 antibody
        • Leukocyte surface antigen p150 95 alpha subunit antibody
        • Leukocyte surface antigen p150 alpha subunit antibody
        • Myeloid membrane antigen alpha subunit antibody
        • p150 95 integrin alpha chain antibody
        • p150 antibody
        • p150/95 antibody
        • SLEB6 antibody
        see all

      Images

      • Flow Cytometry - PE/Cy7® Anti-CD11c antibody [N418] (ab210310)
        Flow Cytometry - PE/Cy7® Anti-CD11c antibody [N418] (ab210310)

        Flow cytometric analysis of C57Bl/6 splenocytes labeling CD11c with FITC Anti-Mouse MHC Class II and 1 ug ab210310 (right panel) or 1 ug PE-Cy7 Armenian Hamster IgG (left panel).

      References (0)

      Publishing research using ab210310? Please let us know so that we can cite the reference in this datasheet.

      ab210310 has not yet been referenced specifically in any publications.

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