Key features and details
- PE/Cy7® Mouse monoclonal [LT95] to FAS Intracellular Fragment
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE/Cy7®. Ex: 496nm, Em: 774nm
- Isotype: IgG1
Product namePE/Cy7® Anti-FAS Intracellular Fragment antibody [LT95]
DescriptionPE/Cy7® Mouse monoclonal [LT95] to FAS Intracellular Fragment
ConjugationPE/Cy7®. Ex: 496nm, Em: 774nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human
Tissue, cells or virus corresponding to FAS Intracellular Fragment. (HUT-78 human T cell lymphoma cell line)
- Flow Cytometry: Human peripheral blood.
This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.
Storage instructionsShipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark.
Storage bufferpH: 7.4
Preservative: 0.0975% Sodium azide
Concentration information loading...
Purification notesab234275 is conjugated with tandem dye PE-Cy™7 under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Our Abpromise guarantee covers the use of ab234275 in the following tested applications.
|Flow Cyt||Use 4µl for 106 cells.|
RelevanceFas is a receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Isoform 1 is located at the cell membrane as a single-pass type I meembrane protein.
Cellular localizationCell Membrane; Single-pass type I membrane protein.
- Entrez Gene: 355 Human
- Apoptosis mediating surface antigen FAS antibody
- APT1 antibody
- TNF receptor superfamily member 6 antibody
- Tumor necrosis factor receptor superfamily member 6 antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab234275 has not yet been referenced specifically in any publications.