Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum as well as purified and partially purified Penicillinase [E. clocae]. Cross reactivity against Penicillinase from other tissues and species may occur but have not been specifically determined.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: 1/7000 - 1/21000 in assay against 1.0ug of Penicillinase [E. clocae] in a standard ELISA.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Penicillinase is a beta-lactamase, showing specificity for penicillins by hydrolysing the beta-lactam ring. Beta lactamases play a significant role in the high resistance of certain organinsms to penicillins, cephalosporins, cephamycins and carbapenems. These antibiotics have a common element in their molecular structure: a four-atom ring known as a beta-lactam. The lactamase enzyme breaks that ring open, deactivating the molecule's antibacterial properties. Penicillinase resistant ß lactams have been developed, such as methicillin, although there is widespread resistance to these now also (MRSA).
Aer 1 antibody
Beta lactamase 1 antibody
Beta lactamase AER 1 antibody
Beta lactamase AER1 antibody
Beta lactamase antibody
Beta lactamase type I antibody
Bla L antibody
OXA 9 antibody
has not yet been referenced specifically in any publications.
Publishing research using ab20959? Please let us know so that we can cite the reference in this datasheet.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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