Overview

  • Product name

    Anti-Pentraxin 3/PTX3 antibody [MNB1]
    See all Pentraxin 3/PTX3 primary antibodies
  • Description

    Rat monoclonal [MNB1] to Pentraxin 3/PTX3
  • Host species

    Rat
  • Tested applications

    Suitable for: ICC/IF, WB, IP, IHC-Fr, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human Pentraxin 3/PTX3.

  • Positive control

    • ICC/IF: MDA-MB-231 cells.
  • General notes

    Previously labelled as Pentraxin 3. 

Properties

Applications

Our Abpromise guarantee covers the use of ab90806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
WB 1/50. Predicted molecular weight: 42 kDa.
IP Use at an assay dependent concentration.
IHC-Fr 1/50.
IHC-P 1/50.

Target

  • Function

    Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.
  • Sequence similarities

    Contains 1 pentaxin domain.
  • Post-translational
    modifications

    Glycosylated.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • AI607804 antibody
    • Pentaxin 3 antibody
    • Pentaxin-related protein PTX3 antibody
    • Pentraxin 3 long antibody
    • Pentraxin-related gene antibody
    • Pentraxin-related gene rapidly induced by IL-1 beta antibody
    • Pentraxin-related protein PTX3 antibody
    • PTX3 antibody
    • PTX3_HUMAN antibody
    • TNF alpha-induced protein 5 antibody
    • TNFAIP5 antibody
    • TSG-14 antibody
    • TSG14 antibody
    • Tumor necrosis factor alpha-induced protein 5 antibody
    • Tumor necrosis factor-inducible gene 14 protein antibody
    • Tumor necrosis factor-inducible protein TSG-14 antibody
    see all

Images

  • ICC/IF image of ab90806 stained MDA-MB-231 cells. The cells were 4% parafrmaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab90806, 1µg/ml) overnight at +4°C. The secondary antibody (green) was ab98420, DyLight® 488 goat anti-rat IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

References

This product has been referenced in:

  • Bendícková K  et al. Calcineurin inhibitors reduce NFAT-dependent expression of antifungal pentraxin-3 by human monocytes. J Leukoc Biol N/A:N/A (2019). Read more (PubMed: 30934147) »
  • Scimeca M  et al. Impairment of PTX3 expression in osteoblasts: a key element for osteoporosis. Cell Death Dis 8:e3125 (2017). WB, IHC, ICC/IF ; Human . Read more (PubMed: 29022895) »
See all 5 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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