PerCP/Cy5.5® Anti-CD11c antibody [N418] (ab111469)
Key features and details
- PerCP/Cy5.5® Armenian hamster monoclonal [N418] to CD11c
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PerCP/Cy5.5®. Ex: 482nm, Em: 690nm
- Isotype: IgG
Overview
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Product name
PerCP/Cy5.5® Anti-CD11c antibody [N418]
See all CD11c primary antibodies -
Description
PerCP/Cy5.5® Armenian hamster monoclonal [N418] to CD11c -
Host species
Armenian hamster -
Conjugation
PerCP/Cy5.5®. Ex: 482nm, Em: 690nm -
Specificity
N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90 kDa heterodimer. -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Preparation of spleen dendritic cells (Mouse)
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Positive control
- Splenocytes.
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General notes
Excitation wavelength: 488 nm. Emission wavelength: 690 nm.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.16% Sodium phosphate, 0.1% Gelatin -
Concentration information loading...
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Purity
Affinity purified -
Clonality
Monoclonal -
Clone number
N418 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
- Anti-CD11c antibody [N418] - Low endotoxin, Azide free (ab185783)
- APC Anti-CD11c antibody [N418] (ab210306)
- APC/Cy7® Anti-CD11c antibody [N418] (ab210307)
- FITC Anti-CD11c antibody [N418] (ab210308)
- PE Anti-CD11c antibody [N418] (ab210309)
- PE/Cy7® Anti-CD11c antibody [N418] (ab210310)
- Alexa Fluor® 647 Anti-CD11c antibody [N418] (ab233046)
- Anti-CD11c antibody [N418] - BSA and Azide free (ab233173)
- violetFluor™ 450 Anti-CD11c antibody [N418] (ab242269)
- Anti-CD11c antibody [N418] (ab33483)
- Alexa Fluor® 488 Anti-CD11c antibody [N418] (ab33503)
- Biotin Anti-CD11c antibody [N418] (ab95765)
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab111469 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt | Use at an assay dependent dilution. This can be used at less than or equal to 0.25µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. |
Target
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Function
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. -
Tissue specificity
Predominantly expressed in monocytes and granulocytes. -
Sequence similarities
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
Domain
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 16411 Mouse
- SwissProt: Q9QXH4 Mouse
- Unigene: 22378 Mouse
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Alternative names
- 95 alpha chain antibody
- 95 antibody
- CD 11c antibody
see all
Images
Datasheets and documents
References (0)
ab111469 has not yet been referenced specifically in any publications.