Overview

  • Product name

    Anti-Peroxiredoxin 2/PRP antibody
    See all Peroxiredoxin 2/PRP primary antibodies
  • Description

    Rabbit polyclonal to Peroxiredoxin 2/PRP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Fr, IHC-Pmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse, Sheep, Cow, Pig, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human Peroxiredoxin 2/PRP (internal sequence). The exact sequence is proprietary.
    Database link: P32119

  • Positive control

    • WB: A549 and HCT 116 whole cell extracts. IHC-P: Human breast cancer tissue. IHC-Fr: Rat liver tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab226922 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 16,22 kDa.
IHC-Fr 1/100 - 1/1000.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
  • Sequence similarities

    Belongs to the ahpC/TSA family.
    Contains 1 thioredoxin domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Epididymis secretory sperm binding protein Li 2a antibody
    • HEL S 2a antibody
    • MGC4104 antibody
    • Natural killer cell enhancing factor B antibody
    • Natural killer cell-enhancing factor B antibody
    • Natural Killer Enhancing Factor B antibody
    • NKEF B antibody
    • NKEF-B antibody
    • NKEFB antibody
    • Peroxiredoxin 2 antibody
    • Peroxiredoxin-2 antibody
    • PRDX 2 antibody
    • PRDX2 antibody
    • PRDX2_HUMAN antibody
    • PrP antibody
    • PRX2 antibody
    • PRXII antibody
    • PTX1 antibody
    • TDPX1 antibody
    • Thiol Specific Antioxidant 1 antibody
    • Thiol specific antioxidant protein antibody
    • Thiol-specific antioxidant protein antibody
    • Thioredoxin Dependent Peroxide Reductase 1 antibody
    • Thioredoxin peroxidase 1 antibody
    • Thioredoxin-dependent peroxide reductase 1 antibody
    • Torin antibody
    • TPX1 antibody
    • TSA antibody
    see all

Images

  • All lanes : Anti-Peroxiredoxin 2/PRP antibody (ab226922) at 1/5000 dilution

    Lane 1 : A549 (human lung carcinoma cell line) whole cell extract
    Lane 2 : NCI-H1299 (human lung carcinoma cell line) whole cell extract
    Lane 3 : HCT 116 (human colorectal carcinoma cell line) whole cell extract

    Lysates/proteins at 30 µg per lane.

    Secondary
    All lanes : HRP-conjugated anti-rabbit IgG

    Predicted band size: 16,22 kDa



    15% SDS-PAGE gel.

  • Frozen section of rat liver tissue stained for Peroxiredoxin 2/PRP using ab226922 at 1/200 dilution in immunohistochemical analysis, followed by a fluorescent secondary antibody.

  • Paraffin-embedded human breast cancer tissue stained for Peroxiredoxin 2/PRP using ab226922 at 1/500 dilution in immunohistochemical analysis.

References

ab226922 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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