PF 356231, MMP-12 inhibitor (ab145237)
Overview
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Product name
PF 356231, MMP-12 inhibitor -
Description
Potent and selective non-chelating MMP-12 inhibitor -
Biological description
Potent and selective non-chelating MMP-12 inhibitor (IC50 = 14 nM). Inhibits other MMPs at higher concentrations. Inhibits cancer cell migration and invasion. -
Purity
> 98% -
CAS Number
766536-21-4 -
Chemical structure
Properties
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Chemical name
3-Phenyl-3-[[4-(4-pyridin-4-ylphenyl)thiophene-2-carbonyl]amino]propanoic acid -
Molecular weight
428.50 -
Molecular formula
C25H20N2O3S -
PubChem identifier
21145408 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C(C=C1)C(CC(=O)O)NC(=O)C2=CC(=CS2)C3=CC=C(C=C3)C4=CC=NC=C4 -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab145237 has not yet been referenced specifically in any publications.
