Overview

  • Product name

    Anti-PF4 antibody [EPR7762]
    See all PF4 primary antibodies
  • Description

    Rabbit monoclonal [EPR7762] to PF4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human PF4 (UniProt ID: P02776).

  • Positive control

    • Human spleen and Human platelet lysates
  • General notes

    Mouse: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab129090 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 11 kDa (predicted molecular weight: 11 kDa).
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function

      Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
    • Sequence similarities

      Belongs to the intercrine alpha (chemokine CxC) family.
    • Post-translational
      modifications

      Binds non-covalently to a proteoglycan molecule.
    • Cellular localization

      Secreted.
    • Information by UniProt
    • Database links

    • Alternative names

      • C-X-C motif chemokine 4 antibody
      • Chemokine (C X C motif) ligand 4 antibody
      • Chemokine (CXC motif) ligand 4 antibody
      • CXCL 4 antibody
      • CXCL4 antibody
      • Iroplact antibody
      • MGC138298 antibody
      • Oncostatin A antibody
      • Oncostatin-A antibody
      • OncostatinA antibody
      • PF 4 antibody
      • PF-4 antibody
      • PF4 antibody
      • Platelet factor 4 antibody
      • PLF4_HUMAN antibody
      • SCYB 4 antibody
      • SCYB4 antibody
      • short form antibody
      • Small inducible cytokine subfamily member 4 antibody
      see all

    Images

    • All lanes : Anti-PF4 antibody [EPR7762] (ab129090) at 1/1000 dilution

      Lane 1 : Human spleen lysate
      Lane 2 : Human platelet lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 11 kDa
      Observed band size: 11 kDa

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab129090 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab129090.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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