Recombinant Anti-PGC1 beta antibody [EPR12370] - BSA and Azide free (ab240188)


  • Product name

    Anti-PGC1 beta antibody [EPR12370] - BSA and Azide free
    See all PGC1 beta primary antibodies
  • Description

    Rabbit monoclonal [EPR12370] to PGC1 beta - BSA and Azide free
  • Host species

  • Tested applications

    Suitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC/IF or IHC-P
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human PGC1 beta aa 950 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: Q86YN6

  • General notes

    ab240188 is the carrier-free version of ab176328 This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    Ab240188 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    This product may be covered by one or more of the following U.S. Patents.


    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.


Our Abpromise guarantee covers the use of ab240188 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 113 kDa.
IP Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
  • Target

    • Function

      Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
    • Tissue specificity

      Ubiquitous with higher expression in heart, brain and skeletal muscle.
    • Sequence similarities

      Contains 1 RRM (RNA recognition motif) domain.
    • Domain

      Contains 2 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which are usually required for the association with nuclear receptors.
    • Cellular localization

    • Information by UniProt
    • Database links

    • Alternative names

      • PERC antibody
      • peroxisome proliferative activated receptor, gamma, coactivator 1, antibody
      • peroxisome proliferator-activated receptor gamma coactivator 1 beta antibody
      • Peroxisome proliferator-activated receptor gamma coactivator 1-beta antibody
      • peroxisome proliferator-activated receptor gamma, coactivator 1 beta antibody
      • PGC-1(beta) antibody
      • PGC-1-beta antibody
      • PGC-1-related estrogen receptor alpha coactivator antibody
      • PGC1 antibody
      • PPAR gamma coactivator-1beta antibody
      • PPAR-gamma coactivator 1-beta antibody
      • PPARGC-1-beta antibody
      • PPARGC1 antibody
      • Ppargc1b antibody
      • PRGC2_HUMAN antibody
      see all


    • ab176328 (purified) at 1/20 immunoprecipitating PGC1 beta in HeLa whole cell lysate.

      Lane 1 (input): HeLa whole cell lysate (10µg)

      Lane 2 (+): ab176328 + HeLa whole cell lysate.

      Lane 3 (-): Rabbit monoclonal IgG (ab172730) instead of ab176328 in HeLa whole cell lysate.

      For western blotting, VeriBlot for IP Detection Reagent (HRP) (ab131366), was used for detection at 1/1000 dilution.

      Blocking buffer and concentration: 5% NFDM/TBST.

      Diluting buffer and concentration: 5% NFDM /TBST.

      This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab176328).

    • Western blot analysis on immunoprecipitation pellet from HeLa cell lysate labeling PGC1 beta using unpurified ab176328 at a dilution of 1/10.

      This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab176328).


    ab240188 has not yet been referenced specifically in any publications.

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