Key features and details
- Rabbit polyclonal to PGE2 receptor EP4 subtype
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-PGE2 receptor EP4 subtype antibody
See all PGE2 receptor EP4 subtype primary antibodies
DescriptionRabbit polyclonal to PGE2 receptor EP4 subtype
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Synthetic peptide within Human PGE2 receptor EP4 subtype aa 161-184 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: P35408
- IHC-P: Human lung carcinoma tissue.
This product was previously labelled as Prostaglandin E Receptor EP4
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 1% BSA, 50% Glycerol
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab217966 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.|
FunctionReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Tissue specificityHigh in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- EP 4 antibody
- EP4 antibody
- EP4R antibody
Anti-PGE2 receptor EP4 subtype antibody (ab217966) at 1/300 dilution + Raji cell lysates
Conjugated secondary antibody at 1/20000 dilution
Immunohistochemical analysis of formalin-fixed paraffin-embedded sections of human lung carcinoma tissue labeling PGE2 receptor EP4 with ab217966 at a 1/200 dilution, followed by conjugation to a secondary antibody and DAB staining.
ab217966 has not yet been referenced specifically in any publications.