Overview

  • Product name

    Anti-PGE2 receptor EP4 subtype antibody
    See all PGE2 receptor EP4 subtype primary antibodies
  • Description

    Rabbit polyclonal to PGE2 receptor EP4 subtype
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human PGE2 receptor EP4 subtype aa 161-184 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: P35408

  • Positive control

    • IHC-P: Human lung carcinoma tissue.
  • General notes

     This product was previously labelled as Prostaglandin E Receptor EP4

     

Properties

Applications

Our Abpromise guarantee covers the use of ab217966 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.
WB 1/300.

Target

  • Function

    Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
  • Tissue specificity

    High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • EP 4 antibody
    • EP4 antibody
    • EP4R antibody
    • MGC126583 antibody
    • PE2R4_HUMAN antibody
    • PGE receptor EP4 subtype antibody
    • PGE2 receptor EP4 subtype antibody
    • Prostaglandin E receptor 4 antibody
    • Prostaglandin E receptor 4 subtype EP4 antibody
    • Prostaglandin E2 receptor antibody
    • Prostaglandin E2 receptor EP4 subtype antibody
    • Prostanoid EP4 receptor antibody
    • PTGER 2 antibody
    • PTGER 4 antibody
    • PTGER2 antibody
    • PTGER4 antibody
    see all

Images

  • Anti-PGE2 receptor EP4 subtype antibody (ab217966) at 1/300 dilution + Raji cell lysates

    Secondary
    Conjugated secondary antibody at 1/20000 dilution
  • Immunohistochemical analysis of formalin-fixed paraffin-embedded sections of human lung carcinoma tissue labeling PGE2 receptor EP4 with ab217966 at a 1/200 dilution, followed by conjugation to a secondary antibody and DAB staining.

References

ab217966 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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