Anti-PGE2 receptor EP4 subtype antibody - C-terminal (ab188761)
Key features and details
- Rabbit polyclonal to PGE2 receptor EP4 subtype - C-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PGE2 receptor EP4 subtype antibody - C-terminal
See all PGE2 receptor EP4 subtype primary antibodies -
Description
Rabbit polyclonal to PGE2 receptor EP4 subtype - C-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Horse, Chicken, Guinea pig, Hamster, Cow, Dog, Chimpanzee, Monkey, Gorilla -
Immunogen
Synthetic peptide corresponding to Human PGE2 receptor EP4 subtype (C terminal). 18 amino acid peptide.
Database link: P35408 -
Positive control
- Human pancreas tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab188761 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 3.6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 3.6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. -
Tissue specificity
High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 427183 Chicken
- Entrez Gene: 450195 Chimpanzee
- Entrez Gene: 282331 Cow
- Entrez Gene: 403589 Dog
- Entrez Gene: 101152623 Gorilla
- Entrez Gene: 100192398 Guinea pig
- Entrez Gene: 100053208 Horse
- Entrez Gene: 5734 Human
see all -
Alternative names
- EP 4 antibody
- EP4 antibody
- EP4R antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab188761 has been referenced in 1 publication.
- Wu H et al. CircARL8B Contributes to the Development of Breast Cancer Via Regulating miR-653-5p/HMGA2 Axis. Biochem Genet N/A:N/A (2021). PubMed: 34050452